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2-Cyanomethylthioadenosine manufacturers
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| | 2-Cyanomethylthioadenosine Basic information |
| Product Name: | 2-Cyanomethylthioadenosine | | Synonyms: | 2-Cyanomethylthioadenosine;2-((6-amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-2-yl)thio)acetonitrile | | CAS: | 2095417-67-5 | | MF: | C12H14N6O4S | | MW: | 338.34 | | EINECS: | | | Product Categories: | | | Mol File: | 2095417-67-5.mol |  |
| | 2-Cyanomethylthioadenosine Chemical Properties |
| Boiling point | 804.7±75.0 °C(Predicted) | | density | 1.97±0.1 g/cm3(Predicted) | | pka | 13.07±0.70(Predicted) |
| | 2-Cyanomethylthioadenosine Usage And Synthesis |
| Uses | 2-Cyanomethylthioadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1]. | | References | [1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
[2] Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500. DOI:10.1016/j.drudis.2021.02.020 |
| | 2-Cyanomethylthioadenosine Preparation Products And Raw materials |
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