JWH 203 N-(5-hydroxypentyl) metabolite

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JWH 203 N-(5-hydroxypentyl) metabolite Basic information
Product Name:JWH 203 N-(5-hydroxypentyl) metabolite
Synonyms:JWH 203 N-(5-hydroxypentyl) metabolite;Ethanone, 2-(2-chlorophenyl)-1-[1-(5-hydroxypentyl)-1H-indol-3-yl]-;2-(2-chlorophenyl)-1-(1-(5-hydroxypentyl)-1H-indol-3-yl)ethan-1-one
CAS:1843184-37-1
MF:C21H22ClNO2
MW:355.86
EINECS:
Product Categories:
Mol File:1843184-37-1.mol
JWH 203 N-(5-hydroxypentyl) metabolite Structure
JWH 203 N-(5-hydroxypentyl) metabolite Chemical Properties
Boiling point 548.6±40.0 °C(Predicted)
density 1.18±0.1 g/cm3(Predicted)
solubility DMF: 10 mg/ml; DMSO: 5 mg/ml
pka15.17±0.10(Predicted)
Safety Information
MSDS Information
JWH 203 N-(5-hydroxypentyl) metabolite Usage And Synthesis
DescriptionJWH 203 is an analgesic chemical from the phenylacetylindole family that acts as a cannabinoid (CB) agonist with Ki values of 8.0 and 7.0 nM at the central (CB1) and peripheral (CB2) receptors, respectively.1 Similar to the related 2'-methoxy compound JWH 250 , JWH 203 has a phenylacetyl group in place of the naphthoyl ring used in most aminoalkylindole CB compounds. Compared to JWH 250, JWH 203 displays slightly more potent binding affinities for the CB1 and CB2 CB receptors (JWH 250 Kis = 11 and 33 nM, respectively).1 JWH 203 N-(5-hydroxypentyl) metabolite is expected to be a metabolite of JWH 203 that would be detectable both in serum and in urine.
References1. Huffman, J.W., Szklennik, P.V., Almond, A., et al. 1-Pentyl-3-phenylacetylindoles, a new class of cannabimimetic indoles Bioorg. Med. Chem. Lett. 15(18),4110-4113(2005).
JWH 203 N-(5-hydroxypentyl) metabolite Preparation Products And Raw materials
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