- GLPG0187
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- $39.00
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2026-08-20
- CAS:1320346-97-1
- Purity: 99.70%
- Supply Ability: 10g
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| | GLPG0187 Basic information |
| Product Name: | GLPG0187 | | Synonyms: | GLPG0187;GLPG0187, 98%, a broad spectrum integrin receptor antagonist with antitumor activity;(S)-3-(2,5-dimethyl-6-(4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)piperidin-1-yl)pyrimidin-4-ylamino)-2-(4-methoxyphenylsulfonamido)propanoic acid;CS-2550;GLPG 0187;GLPG-0187;L-Alanine, 3-[[2,5-dimethyl-6-[4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)-1-piperidinyl]-4-pyrimidinyl]amino]-N-[(4-methoxyphenyl)sulfonyl]-;inhibit,GLPG-0187,GLPG0187,GLPG 0187,Inhibitor,Integrin;(2S)-3-({2,5-dimethyl-6-[4-(1,5,6,7-tetrahydro-1,8-naphthyridin-2-yl)piperidin-1-yl]pyrimidin-4-yl}amino)-2-(4-methoxybenzenesulfonamido)propanoic acid | | CAS: | 1320346-97-1 | | MF: | C29H37N7O5S | | MW: | 595.71 | | EINECS: | | | Product Categories: | | | Mol File: | 1320346-97-1.mol |  |
| | GLPG0187 Chemical Properties |
| Boiling point | 894.7±75.0 °C(Predicted) | | density | 1.43±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO:8.0(Max Conc. mg/mL);13.43(Max Conc. mM) | | form | A crystalline solid | | pka | 2.86±0.10(Predicted) | | color | White to off-white |
| | GLPG0187 Usage And Synthesis |
| Uses | GLPG-0187 is an integrin receptor antagonist which displays anti-tumor activity. | | in vivo | Blocking αv-integrins by GLPG0187 markedly reduces their metastatic tumor growth. Bone tumor burden is significantly lower and the number of bone metastases/mouse is significantly inhibited. The progression of bone metastases and the formation of new bone metastases during the treatment period is significantly inhibited[1]. | | storage | Store at -20°C |
| | GLPG0187 Preparation Products And Raw materials |
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