- Gcase activator 1
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- $58.00 / 5mg
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2026-03-09
- CAS:1919820-28-2
- Min. Order:
- Purity: 99.31%
- Supply Ability: 10g
- LTI-291
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- $1.00 / 1g
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2019-12-26
- CAS:1919820-28-2
- Min. Order: 1g
- Purity: 99%
- Supply Ability: 200kg
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| | LTI-291 Basic information |
| Product Name: | LTI-291 | | Synonyms: | LTI-291;5,7-dimethyl-N-((1r,4r)-4-(pentyloxy)cyclohexyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;184658;LTI291;LTI 291;CS-2568;TI-291;Pyrazolo[1,5-a]pyrimidine-3-carboxamide, 5,7-dimethyl-N-[trans-4-(pentyloxy)cyclohexyl]-;5,7-dimethyl-N-(trans-4-(pentyloxy)cyclohexyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide | | CAS: | 1919820-28-2 | | MF: | C20H30N4O2 | | MW: | 358.48 | | EINECS: | | | Product Categories: | | | Mol File: | 1919820-28-2.mol |  |
| | LTI-291 Chemical Properties |
| density | 1.21±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMF: 30 mg/ml; DMSO: 20 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS (pH 7.2) (1:4): 0.2 mg/ml | | form | A solid | | pka | 11.03±0.40(Predicted) | | color | White to off-white |
| | LTI-291 Usage And Synthesis |
| Uses | Gcase activator 1 is an activator of glucocerebrosidase (Gcase), with activation rates of more than 60% (1 μM) and between 10%-20% (0.1 μM). Gcase activator 1 can be used for Parkinson's disease and endometriosis research[1]. | | References | [1] Renato T. Skerlj, et al. Methods of treatment and combination therapies using gcase activator heterobicyclic and related compounds. WO 2017192841 A1. |
| | LTI-291 Preparation Products And Raw materials |
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