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| | Cytosolic protamine kinase Basic information |
| Product Name: | Cytosolic protamine kinase | | Synonyms: | PROTAMINE KINASE, CYTOSOLIC BOVINE KIDNEY;Protamine Kinase, Cytosolic from bovine kidney;DKFZp686L193;MGC142218;PI3-K-C2(ALPHA);PI3-K-C2A;PIK3C2A, active, GST tagged human;CPK | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![Cytosolic protamine kinase Structure]() |
| | Cytosolic protamine kinase Chemical Properties |
| storage temp. | −70°C | | form | buffered aqueous glycerol solution | | Specific Activity | 16.2-25.3nmol/min·mg |
| WGK Germany | 1 | | Storage Class | 10 - Combustible liquids |
| | Cytosolic protamine kinase Usage And Synthesis |
| Uses | Cytosolic Protamine Kinase (cPK) is isolated from bovine kidney and has a molecular mass of approximately 45 kDa. It phosphorylates the eukaryotic Initiation Factor 4E (eIF4E), which initiates translation by mRNA. It is used to study protein synthesis and various cellular processes. | | Biological Activity | Cytosolic protamine kinase is involved in the regulation of protein synthesis and is indirectly associated with numerous cellular processes. Cytosolic protamine kinase is a distinct insulin-stimulated kinase involved in the phosphorylation of eukaryotic Initiation Factor 4E (eIF4E) which is key to initiating translation by mRNA. This protein appears to be inactivated by protein phosphatase 2A family members and may also be inhibited by microcystin, okadeic acid, and ATP. The phosphorylation process is reversible and MBPK1 and MBPK2 (Myelin Basic Protein Kinase 1 and 2) may reactivate cytosolic protamine kinase . |
| | Cytosolic protamine kinase Preparation Products And Raw materials |
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