7H-Pyrrolo[2,3-d]pyrimidine-5-carboximidicacid, 4-amino-7-b-D-ribofuranosyl-,hydrazide

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Company Name: NewCan Biotech Limited  
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Company Name: TargetMol Chemicals Inc.  
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Email: marketing@targetmol.com
Company Name: TargetMol Chemicals Inc.  
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Email: marketing@targetmol.cn
Company Name: TargetMol Chemicals Inc.  
Tel: 13564774135
Email: marketing@targetmol.com

7H-Pyrrolo[2,3-d]pyrimidine-5-carboximidicacid, 4-amino-7-b-D-ribofuranosyl-,hydrazide manufacturers

  • SLM6
  • SLM6 pictures
  • $1980.00
  • 2026-07-27
  • CAS:22242-91-7
  • Purity:
  • Supply Ability: 10g
7H-Pyrrolo[2,3-d]pyrimidine-5-carboximidicacid, 4-amino-7-b-D-ribofuranosyl-,hydrazide Basic information
Product Name:7H-Pyrrolo[2,3-d]pyrimidine-5-carboximidicacid, 4-amino-7-b-D-ribofuranosyl-,hydrazide
Synonyms:7H-Pyrrolo[2,3-d]pyrimidine-5-carboximidicacid, 4-amino-7-b-D-ribofuranosyl-,hydrazide;NSC 107517;NSC-107517;Sangivamycin-Like Molecule 6;SLM 6;SLM6;SLM-6;7H-Pyrrolo[2,3-d]pyrimidine-5-carboximidic acid, 4-amino-7-β-D-ribofuranosyl-, hydrazide
CAS:22242-91-7
MF:C12H17N7O4
MW:323.30788
EINECS:
Product Categories:
Mol File:22242-91-7.mol
7H-Pyrrolo[2,3-d]pyrimidine-5-carboximidicacid, 4-amino-7-b-D-ribofuranosyl-,hydrazide Structure
7H-Pyrrolo[2,3-d]pyrimidine-5-carboximidicacid, 4-amino-7-b-D-ribofuranosyl-,hydrazide Chemical Properties
Boiling point 725.3±70.0 °C(Predicted)
density 2.10±0.1 g/cm3(Predicted)
pka12.38±0.70(Predicted)
Safety Information
MSDS Information
7H-Pyrrolo[2,3-d]pyrimidine-5-carboximidicacid, 4-amino-7-b-D-ribofuranosyl-,hydrazide Usage And Synthesis
DescriptionSLM6 is an inhibitor of cyclin-dependent kinase-9 (CDK9). It exhibits potent anti-multiple myeloma activity.
UsesSLM6 is a sangivamycin-like molecule. SLM6 is a CDK9 inhibitor. SLM6 inhibits CDK9/cyclin K and CDK9/cyclin T1 kinase activity with IC50s of 280 nM and 133 nM, respectively. SLM6 also inhibits CDK1/cyclin B and CDK2/ cyclin A with IC50s of less than 300 nM. SLM6 induces apoptosis in multiple myeloma (MM) cells[1].
IC 50CDK9/cyclinT1: 133 nM (IC50)
References[1] Villanueva-Gutierrez EE, et al. Simple Sequence Repeat Markers Reveal Genetic Diversity and Population Structure of Bolivian Wild and Cultivated Tomatoes (Solanum lycopersicum L.). Genes (Basel). 2022 Aug 23;13(9):1505. DOI:10.3390/genes13091505
7H-Pyrrolo[2,3-d]pyrimidine-5-carboximidicacid, 4-amino-7-b-D-ribofuranosyl-,hydrazide Preparation Products And Raw materials
Tag:7H-Pyrrolo[2,3-d]pyrimidine-5-carboximidicacid, 4-amino-7-b-D-ribofuranosyl-,hydrazide(22242-91-7) Related Product Information
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