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- 3-Iodobenzylamine hcl
-
- $9.00
-
2026-05-28
- CAS:3718-88-5
- Min. Order: 1KG
- Purity: 99.8%
- Supply Ability: 100tons
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| | 3-Iodobenzylamine hydrochloride Basic information |
| | 3-Iodobenzylamine hydrochloride Chemical Properties |
| Melting point | 188-190 °C(lit.) | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | Water Solubility | Soluble in water | | form | powder to crystal | | color | White to Light yellow | | Sensitive | Light Sensitive | | BRN | 5352277 | | InChI | InChI=1S/C7H8IN.ClH/c8-7-3-1-2-6(4-7)5-9;/h1-4H,5,9H2;1H | | InChIKey | PYFDZOCGFHIRST-UHFFFAOYSA-N | | SMILES | C(C1C=CC=C(I)C=1)N.Cl | | CAS DataBase Reference | 3718-88-5(CAS DataBase Reference) |
| Hazard Codes | Xi,T,Xn | | Risk Statements | 36/37/38-63-42/43 | | Safety Statements | 24/25-36/37/39-26-23-22 | | WGK Germany | 3 | | Hazard Note | Irritant/Light Sensitive | | HS Code | 29214990 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Eye Irrit. 2
Repr. 2
Resp. Sens. 1
Skin Irrit. 2
Skin Sens. 1
STOT SE 3 |
| | 3-Iodobenzylamine hydrochloride Usage And Synthesis |
| Chemical Properties | white to light yellow crystal powde | | Uses | 3-Iodobenzylamine hydrochloride was used as the starting reagent in the synthesis of N6-(3-iodobenzyl)-2-substituted-adenosine derivatives. It was used in the synthesis of 3′-C-methyl adenosine N6-substituted and N6/C-2 disubstituted derivatives and novel 2′-C-methyl analogues. | | Synthesis | The general procedure for the synthesis of 3-iodobenzylamine hydrochloride from the compound (CAS: 200706-60-1) was as follows: 2.0 g (5.6 mmol) of compound (A) and 20 mL of anhydrous ethanol were added to the reaction flask. After heating the mixture to 60°C, an ethanolic solution of hydrazine hydrate (prepared by dissolving 0.42 g, 8.4 mmol of hydrazine hydrate in 3 mL of anhydrous ethanol) was added dropwise under continuous stirring. The reaction was kept heated and stirred for 20 min and a yellow precipitate was observed to be formed. Stirring was stopped and the reaction mixture was kept in a 70°C water bath for 2.5 hours. It was then cooled to room temperature, at which time a large amount of yellow precipitate precipitated. 4 mL of 1 mol/L hydrochloric acid solution was added to the reaction flask to acidify the reaction mixture and stirring was continued for 30 minutes. After completion of the reaction, a filtration operation was carried out, the filtrate was washed with a small amount of water and the filtrates were combined. The combined filtrates were evaporated to dryness under reduced pressure and finally dried under vacuum to give 0.539 g of yellow solid (B) in 35.9% yield. | | References | [1] Patent: CN106187823, 2016, A. Location in patent: Paragraph 0028; 0029 |
| | 3-Iodobenzylamine hydrochloride Preparation Products And Raw materials |
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