2-(2-((tert-Butoxycarbonyl)amino)ethoxy)-ethyl 4-methylbenzenesulfonate

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2-(2-((tert-Butoxycarbonyl)amino)ethoxy)-ethyl 4-methylbenzenesulfonate manufacturers

  • NHBoc-PEG2-Tos
  • NHBoc-PEG2-Tos pictures
  • 2025-06-07
  • CAS:192132-77-7
  • Min. Order: 5g
  • Purity: >98.00%
  • Supply Ability: 5g
2-(2-((tert-Butoxycarbonyl)amino)ethoxy)-ethyl 4-methylbenzenesulfonate Basic information
Product Name:2-(2-((tert-Butoxycarbonyl)amino)ethoxy)-ethyl 4-methylbenzenesulfonate
Synonyms:2-(2-((tert-Butoxycarbonyl)amino)ethoxy)-ethyl 4-methylbenzenesulfonate;NHBoc-PEG2-Tos;BocNH-PEG2-Tos;BocNH-PEG2-Tos/Carbamic acid, N-[2-[2-[[(4-methylphenyl)sulfonyl]oxy]ethoxy]ethyl]-, 1,1-dimethylethyl ester;Carbamic acid, N-[2-[2-[[(4-methylphenyl)sulfonyl]oxy]ethoxy]ethyl]-, 1,1-dimethylethyl ester;t-Boc-N-amido-PEG2-Tos;2-(2-((tert-Butoxycarbonyl)amino)ethoxy)ethyl 4-methylbenzenesulfonate , Tos-PEG2-NH-Boc;BocNH-PEG2-OTos
CAS:192132-77-7
MF:C16H25NO6S
MW:359.44
EINECS:
Product Categories:
Mol File:192132-77-7.mol
2-(2-((tert-Butoxycarbonyl)amino)ethoxy)-ethyl 4-methylbenzenesulfonate Structure
2-(2-((tert-Butoxycarbonyl)amino)ethoxy)-ethyl 4-methylbenzenesulfonate Chemical Properties
Boiling point 504.6±40.0 °C(Predicted)
density 1.179±0.06 g/cm3(Predicted)
storage temp. Storage temp. 2-8°C
solubility DMSO: 250 mg/mL (695.53 mM)
form Solid
pka12.19±0.46(Predicted)
color White to off-white
Safety Information
MSDS Information
2-(2-((tert-Butoxycarbonyl)amino)ethoxy)-ethyl 4-methylbenzenesulfonate Usage And Synthesis
UsesTos-PEG2-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Biological ActivityTos-PEG2-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50PEGs; Alkyl/ether
References[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.
2-(2-((tert-Butoxycarbonyl)amino)ethoxy)-ethyl 4-methylbenzenesulfonate Preparation Products And Raw materials
Tag:2-(2-((tert-Butoxycarbonyl)amino)ethoxy)-ethyl 4-methylbenzenesulfonate(192132-77-7) Related Product Information
2-(2-Boc-aminoethoxy)ethanol Toluene-4-sulfonic acid 2-(2-benzyloxycarbonylamino-ethoxy)-ethyl ester 5,8,11-Trioxa-2-azatridecanoic acid, 13-[[(4-methylphenyl)sulfonyl]oxy]-, 1,1-dimethylethyl ester PROTAC Linker 9 5,8,11,14-Tetraoxa-2-azahexadecanoic acid, 16-[[(4-methylphenyl)sulfonyl]oxy]-, 1,1-dimethylethyl ester tert-butyl N-methyl-N-(2-{2-[(4-methylbenzenesulfonyl)oxy]ethoxy}ethyl)carbamate