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| | SZ1676 Chemical Properties |
| storage temp. | Store at -20°C | | solubility | Soluble in DMSO |
| | SZ1676 Usage And Synthesis |
| Uses | SZ1676 is a derivative of SZ1677, which is a neuromuscular blocking agent. | | in vivo | SZ1676 is the 3-acetoxy derivative[1]. The neuromuscular (NM) effects of SZ1676 and SZ1677 are compared in beagle dogs. SZ1677 (ED90=19.2±2.6 μg/kg) is 1.86 times more potent than SZ1676 (ED90=35.8±2.5 μg/kg)[2]. | | References | [1] Bazewicz A, et al. Application of high-performance liquid chromatography with amperometric and coulometric detection to the analysis of SZ1677, a new neuromuscular blocking agent, and its two derivatives. J Chromatogr A. 2008 Sep 12;1204(1):114-8. DOI:10.1016/j.chroma.2008.07.054
[2] Francis F. Foldes, et al. Comparison of the Neuromuscular Effects of SZ1676, SZ1677 and Vecuronium in Beagle Dogs. Muscle Relaxants pp 379-379. |
| | SZ1676 Preparation Products And Raw materials |
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