mycothiazole

Request For Quotation
mycothiazole Suppliers list
Company Name: TargetMol  
Tel: 400-821-0310 15002144251
Email: xuexiang.shao@tsbiochem.com
mycothiazole Basic information
Product Name:mycothiazole
Synonyms:mycothiazole
CAS:114582-75-1
MF:C22H32N2O3S
MW:404.57
EINECS:
Product Categories:
Mol File:114582-75-1.mol
mycothiazole Structure
mycothiazole Chemical Properties
Safety Information
MSDS Information
mycothiazole Usage And Synthesis
DescriptionMycothiazole is from cacospongia mycofijiensis.
UsesMycothiazole is an inhibitor for mitochondrial electron transport chain (ETC) complex I. Mycothiazole exhibits cytotoxicity in cancer cells Huh7 (IC50 is 55.8 μM), U87 and MCF7. Mycothiazole induces apoptosis in Huh7. Mycothiazole utilizes the unfolded protein response (UPR) and heat shock response (HSR) pathway involved transcription factors ATFS-1 and HSF1, to extend the lifespan of C. elegans[1].
DefinitionChEBI: Mycothiazole is a member of thiazoles. It has a role as a metabolite.
References[1] Dutta N,et al., Investigating impacts of the mycothiazole chemotype as a chemical probe for the study of mitochondrial function and aging. Geroscience. 2024 Apr 3. DOI:10.1007/s11357-024-01144-w
mycothiazole Preparation Products And Raw materials
Tag:mycothiazole(114582-75-1) Related Product Information
FCCP Carbonyl cyanide 3-chlorophenylhydrazone 2-cyano-3-(1-phenylindol-3-yl)acrylate Dimethyl 2-oxoglutarate PERHEXILINE MALEATE SALT Glibenclamide