| Company Name: |
Shanghai YuanYe Biotechnology Co., Ltd.
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| Tel: |
021-61312847; 18021002903 |
| Email: |
3008007409@qq.com |
| Products Intro: |
Product Name:Millepachine
CAS:1393922-01-4
Package:10mg;1g Remarks:S20568
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millepachine manufacturers
- Millepachine
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- $44.00 / 1mg
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2026-04-22
- CAS:1393922-01-4
- Min. Order:
- Purity: 99.73%
- Supply Ability: 10g
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| | millepachine Basic information |
| Product Name: | millepachine | | Synonyms: | millepachine;(E)-1-(5-methoxy-2,2-dimethyl-2H-chromen-8-yl)-3-(4-methoxyphenyl)-prop-2-en-1-one;2-Propen-1-one, 1-(5-methoxy-2,2-dimethyl-2H-1-benzopyran-8-yl)-3-(4-methoxyphenyl)-, (2E)-;Chinese,Millepachine,Millettia,bioactive,chalcone,medicine,natural,Inhibitor,pachycarpa,inhibit,antitumor,herbal,Benth,Apoptosis,cancer;(2E)-1-(5-methoxy-2,2-dimethyl-2H-chromen-8-yl)-3-(4-methoxyphenyl)prop-2-en-1-one;Millepachine, 10 mM in DMSO | | CAS: | 1393922-01-4 | | MF: | C22H22O4 | | MW: | 350.41 | | EINECS: | | | Product Categories: | | | Mol File: | 1393922-01-4.mol |  |
| | millepachine Chemical Properties |
| Boiling point | 528.2±50.0 °C(Predicted) | | density | 1.139±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | form | Solid | | color | Light yellow to yellow |
| | millepachine Usage And Synthesis |
| Uses | Millepachine is a bioactive natural chalcone from Chinese herbal medicine Millettia pachycarpa Benth, exhibits strong antitumor effects against numerous human cancer cells both in vitro and in vivo[1]. | | in vivo | Millepachine (20 mg/kg; i.v. every two days for 14 day) inhibits tumor growth in mice[1].
Millepachine (20 mg/kg; i.v. every two days for 14 day) does not induce acquired drug resistance in an excised A2780S xenograft model[1]. | Animal Model: | Female BALB/c nude mice (6 weeks) are injected A2780S or A2780CP cells[1] | | Dosage: | 20 mg/kg | | Administration: | I.v. every two days for 2-14 days | | Result: | Reduced tumor volume and tumor weight with the inhibitory rate of 73.21% and 65.58% in A2780S (after seven times injection) and A2780CP (after six times injection) xenograft model, respectively.
With low toxicity in vivo.
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| | References | [1] Wu W, et, al. Millepachine showed novel antitumor effects in cisplatin-resistant human ovarian cancer through inhibiting drug efflux function of ATP-binding cassette transporters. Phytother Res. 2018 Dec; 32(12):2428-2435. DOI:10.1002/ptr.6180 |
| | millepachine Preparation Products And Raw materials |
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