| Company Name: |
BOC Sciences |
| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
N,N'-1,2-ethanediylbis[2-(4-tert-butylphenoxy)acetamide] manufacturers
- NIC3
-
- $38.00
-
2026-08-08
- CAS:494830-67-0
- Purity: 98.78%
- Supply Ability: 10g
- NIC3
-
- $38.00
-
2026-08-08
- CAS:494830-67-0
- Purity: 98.78%
- Supply Ability: 10g
|
| | N,N'-1,2-ethanediylbis[2-(4-tert-butylphenoxy)acetamide] Basic information |
| Product Name: | N,N'-1,2-ethanediylbis[2-(4-tert-butylphenoxy)acetamide] | | Synonyms: | N,N'-1,2-ethanediylbis[2-(4-tert-butylphenoxy)acetamide];N,N'-ethane-1,2-diylbis[2-(4-tert-butylphenoxy)acetamide];Acetamide, N,N'-1,2-ethanediylbis[2-[4-(1,1-dimethylethyl)phenoxy]-;inhibit,NIC 3,NIC-3,Inhibitor,NIC3;N,N'-(Ethane-1,2-diyl)bis(2-(4-(tert-butyl)phenoxy)acetamide);NIC3, 10 mM in DMSO | | CAS: | 494830-67-0 | | MF: | C26H36N2O4 | | MW: | 440.58 | | EINECS: | | | Product Categories: | | | Mol File: | 494830-67-0.mol | ![N,N'-1,2-ethanediylbis[2-(4-tert-butylphenoxy)acetamide] Structure](CAS/20180528/GIF/494830-67-0.gif) |
| | N,N'-1,2-ethanediylbis[2-(4-tert-butylphenoxy)acetamide] Chemical Properties |
| storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | form | Solid | | color | White to off-white |
| | N,N'-1,2-ethanediylbis[2-(4-tert-butylphenoxy)acetamide] Usage And Synthesis |
| Uses | NIC3 is a selective nucleus accumbens-associated protein-1 (NAC1) inhibitor, binds to the conserved Leu-90 of NAC1, prevents its homodimerization, and leads to proteasomal NAC1 degradation. Anti-cancer activity[1]. | | References | [1] Wang X, et al. Identification of a small-molecule compound that inhibits homodimerization of oncogenic NAC1 protein and sensitizes cancer cells to anticancer agents. J Biol Chem. 2019 May 17. pii: jbc.RA119.007664. DOI:10.1074/jbc.RA119.007664 |
| | N,N'-1,2-ethanediylbis[2-(4-tert-butylphenoxy)acetamide] Preparation Products And Raw materials |
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