9-(3-hydroxyphenyl)-8-phenyl-4,9-dihydrotetraazolo[1',5':1,2]pyrimido[4,5-d]pyridazin-5-ol

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9-(3-hydroxyphenyl)-8-phenyl-4,9-dihydrotetraazolo[1',5':1,2]pyrimido[4,5-d]pyridazin-5-ol Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Products Intro: Product Name:Pfn1-IN-C2；Pfn1 IN C2;Pfn1INC2;Pfn1 inhibitor C2
CAS:919010-22-3
Package:100 mg；500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: TargetMol Chemicals Inc.
Tel: +17819995354
Email: marketing@targetmol.com
Products Intro: Product Name:Pfn1-IN-C2
CAS:919010-22-3
Package:25mg;1520USD|100mg;2500USD|50mg;1980USD
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Products Intro: Product Name:Pfn1-IN-C2
CAS:919010-22-3
Package:25mg/RMB 10600;100mg/RMB 17500;50mg/RMB 13800
Company Name: Specs  
Tel: +31 15 251 8111
Email: info@specs.net
Products Intro: Product Name:9-(3-hydroxyphenyl)-8-phenyl-4,9-dihydrotetraazolo[1',5':1,2]pyrimido[4,5-d]pyridazin-5-ol
CAS:919010-22-3
Package:1mg

9-(3-hydroxyphenyl)-8-phenyl-4,9-dihydrotetraazolo[1',5':1,2]pyrimido[4,5-d]pyridazin-5-ol manufacturers

  • Pfn1-IN-C2
  • Pfn1-IN-C2 pictures
  • $1520.00
  • 2026-05-11
  • CAS:919010-22-3
  • Purity:
  • Supply Ability: 10g
9-(3-hydroxyphenyl)-8-phenyl-4,9-dihydrotetraazolo[1',5':1,2]pyrimido[4,5-d]pyridazin-5-ol Basic information
Product Name:9-(3-hydroxyphenyl)-8-phenyl-4,9-dihydrotetraazolo[1',5':1,2]pyrimido[4,5-d]pyridazin-5-ol
Synonyms:9-(3-hydroxyphenyl)-8-phenyl-4,9-dihydrotetraazolo[1',5':1,2]pyrimido[4,5-d]pyridazin-5-ol;Pfn1 IN C2;Pfn1 inhibitor C2;Pfn1INC2;Pfn1-IN-C2;Pfn1 IN C2,Pfn1INC2,Pfn-1-IN-C2;Tetrazolo[1',5':1,2]pyrimido[4,5-d]pyridazin-5(6H)-one, 1,9-dihydro-9-(3-hydroxyphenyl)-8-phenyl-
CAS:919010-22-3
MF:C18H13N7O2
MW:359.34
EINECS:
Product Categories:
Mol File:919010-22-3.mol
9-(3-hydroxyphenyl)-8-phenyl-4,9-dihydrotetraazolo[1',5':1,2]pyrimido[4,5-d]pyridazin-5-ol Structure
9-(3-hydroxyphenyl)-8-phenyl-4,9-dihydrotetraazolo[1',5':1,2]pyrimido[4,5-d]pyridazin-5-ol Chemical Properties
density 1.68±0.1 g/cm3(Predicted)
pka9.08±0.60(Predicted)
Safety Information
MSDS Information
9-(3-hydroxyphenyl)-8-phenyl-4,9-dihydrotetraazolo[1',5':1,2]pyrimido[4,5-d]pyridazin-5-ol Usage And Synthesis
DescriptionPfn1-IN-C2 is an inhibitor of Profilin1 (Pfn1). It has been shown to reduce the overall level of cellular filamentous (F)-actin, slow EC migration and proliferation, and inhibit the angiogenic ability of EC both in vitro and ex vivo.
UsesPfn1-IN-2 is an inhibitor of Profilin1 (Pfn1) and has the activity to interfere with the interaction between Pfn1 and actin. Pfn1-IN-2 can significantly reduce the overall level of intracellular filamentous (F) actin. Pfn1-IN-2 also slows down the migration and proliferation of endothelial cells (EC). Pfn1-IN-2 can inhibit the angiogenic ability of endothelial cells both in vivo and in vitro[1].
References[1] Structure-based virtual screening identifies a small-molecule inhibitor of the profilin 1-actin interaction
9-(3-hydroxyphenyl)-8-phenyl-4,9-dihydrotetraazolo[1',5':1,2]pyrimido[4,5-d]pyridazin-5-ol Preparation Products And Raw materials
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