|
|
| | 4-Bromo-o-xylene Basic information |
| | 4-Bromo-o-xylene Chemical Properties |
| Melting point | −12-−10 °C | | Boiling point | 215 °C (lit.) | | density | 1.37 g/mL at 25 °C (lit.) | | refractive index | n20/D 1.555(lit.) | | Fp | 177 °F | | storage temp. | Store below +30°C. | | form | clear liquid | | color | Colorless to Light yellow | | Specific Gravity | 1.37 | | Water Solubility | Not miscible in water. | | BRN | 2040354 | | InChI | 1S/C8H9Br/c1-6-3-4-8(9)5-7(6)2/h3-5H,1-2H3 | | InChIKey | QOGHRLGTXVMRLM-UHFFFAOYSA-N | | SMILES | Cc1ccc(Br)cc1C | | CAS DataBase Reference | 583-71-1(CAS DataBase Reference) | | NIST Chemistry Reference | Benzene, 4-bromo-1,2-dimethyl-(583-71-1) | | EPA Substance Registry System | Benzene, 4-bromo-1,2-dimethyl- (583-71-1) |
| Hazard Codes | Xn,N,Xi | | Risk Statements | 22-36/37/38-50/53 | | Safety Statements | 26-60-61-24/25 | | RIDADR | UN 1701 6.1/PG 2 | | WGK Germany | 3 | | RTECS | CY9020400 | | F | 19 | | Hazard Note | Irritant | | TSCA | TSCA listed | | HazardClass | 9 | | HS Code | 29036990 | | Storage Class | 6.1A - Combustible acute toxic Cat. 1 and 2
very toxic hazardous materials | | Hazard Classifications | Acute Tox. 4 Oral
Aquatic Acute 1
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| | 4-Bromo-o-xylene Usage And Synthesis |
| Chemical Properties | Clear colourless to light yellow liquid | | Uses | 4-Bromo-o-xylene is used as synthetic organic materials and soluble polyimide resin intermediates. | | Synthesis | A method for the preparation of 4-bromo-1,2-xylene, the method uses o-xylene as raw material, in the presence of dichloromethane solvent and catalyst, dropwise addition of bromine at a temperature of -60 ?? to -20 ??, o-xylene and bromine molar ratio of 1:1, after the dropwise addition is completed, hold the temperature to carry out the reaction, and then slowly raise the temperature to 10-20 ??, to remove the dissolved hydrogen bromide in the reaction solution, add saturated aqueous solution of sodium sulfite , stirring for 30 minutes, the product containing dichloromethane was recovered by layering, and then washed with 5% dilute alkali solution to PH = 8-9, and finally washed with water to neutral, to obtain colorless or light yellow 4-bromo-1,2-xylene crude product, distillation under atmospheric pressure to recover solvent dichloromethane, and then distillation under reduced pressure to obtain 4-bromo-1,2-xylene product, said catalyst is a mixture of ferric chloride and quaternary ammonium salt, and the catalyst is a mixture of ferric chloride and quaternary ammonium salt. The quaternary ammonium salt is for example: tetrabutyl ammonium chloride, tetrabutyl ammonium bromide, tetrapropyl ammonium bromide, methyltrioctyl ammonium chloride, benzyltriethylammonium chloride, and the mass ratio of ferric trichloride and the quaternary ammonium salt is 4-5:1. The content of the obtained 4-bromo-1,2-xylene is increased to 85-93%, and at the same time, the content of the byproduct is reduced, and the yield of the product is increased to 95%. Duration of bromine addition: 3-4 h. Holding time of reaction: 2 h. Temperature of alkaline washing: room temperature. |
| | 4-Bromo-o-xylene Preparation Products And Raw materials |
|