(2E)-3-[4-(benzyloxy)phenyl]-1-(4-ethoxyphenyl)prop-2-en-1-one

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(2E)-3-[4-(benzyloxy)phenyl]-1-(4-ethoxyphenyl)prop-2-en-1-one Basic information
Product Name:(2E)-3-[4-(benzyloxy)phenyl]-1-(4-ethoxyphenyl)prop-2-en-1-one
Synonyms:(2E)-3-[4-(benzyloxy)phenyl]-1-(4-ethoxyphenyl)prop-2-en-1-one;2-Propen-1-one, 1-(4-ethoxyphenyl)-3-[4-(phenylmethoxy)phenyl]-;hMAO-B-IN-5;3-(4-(Benzyloxy)phenyl)-1-(4-ethoxyphenyl)prop-2-en-1-one;hMAO-B-IN-5, 10 mM in DMSO
CAS:358343-63-2
MF:C24H22O3
MW:358.43
EINECS:
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Mol File:358343-63-2.mol
(2E)-3-[4-(benzyloxy)phenyl]-1-(4-ethoxyphenyl)prop-2-en-1-one Structure
(2E)-3-[4-(benzyloxy)phenyl]-1-(4-ethoxyphenyl)prop-2-en-1-one Chemical Properties
Boiling point 546.405±50.00 °C(Press: 760.00 Torr)(predicted)
density 1.138±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
form Solid
color White to off-white
Safety Information
MSDS Information
(2E)-3-[4-(benzyloxy)phenyl]-1-(4-ethoxyphenyl)prop-2-en-1-one Usage And Synthesis
UseshMAO-B-IN-5(B15) is a potent, selective and reversible inhibitor of human monoamine oxidase hMAO-B with IC50 of 0.12 μM. hMAO-B-IN-5 can pass through the blood-brain barrier and can be used in the research of neurodegenerative diseases[1].
References[1] Sachithra Thazhathuveedu Sudevan, et al. Introduction of benzyloxy pharmacophore into aryl/heteroaryl chalcone motifs as a new class of monoamine oxidase B inhibitors. Sci Rep. 2022 Dec 27;12(1):22404. DOI:10.1038/s41598-022-26929-x
(2E)-3-[4-(benzyloxy)phenyl]-1-(4-ethoxyphenyl)prop-2-en-1-one Preparation Products And Raw materials
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