1L-6-hydroxymethyl-chiro-inositol 2-(R)-2-O-methyl-3-O-octadecylcarbonate

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1L-6-hydroxymethyl-chiro-inositol 2-(R)-2-O-methyl-3-O-octadecylcarbonate Suppliers list
Company Name: SPIRO PHARMA  
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Email: eric_feng1954@126.com
Company Name: Guangzhou QiYun Biotechnology Co., Ltd.  
Tel: 020-61288194 61288195
Email: 505721671@qq.com
1L-6-hydroxymethyl-chiro-inositol 2-(R)-2-O-methyl-3-O-octadecylcarbonate Basic information
Product Name:1L-6-hydroxymethyl-chiro-inositol 2-(R)-2-O-methyl-3-O-octadecylcarbonate
Synonyms:AKT INHIBITOR;AKT protein kinase inhibitor;1L-6-hydroxymethyl-chiro-inositol 2-(R)-2-O-methyl-3-O-octadecylcarbonate
CAS:1004990-28-6
MF:
MW:0
EINECS:
Product Categories:
Mol File:1004990-28-6.mol
1L-6-hydroxymethyl-chiro-inositol 2-(R)-2-O-methyl-3-O-octadecylcarbonate Structure
1L-6-hydroxymethyl-chiro-inositol 2-(R)-2-O-methyl-3-O-octadecylcarbonate Chemical Properties
storage temp. -20°C
solubility DMSO: 200mg/mL
form solid
color white to off-white
Safety Information
WGK Germany WGK 1
Storage Class11 - Combustible Solids
MSDS Information
1L-6-hydroxymethyl-chiro-inositol 2-(R)-2-O-methyl-3-O-octadecylcarbonate Usage And Synthesis
UsesA cell permeable, reversible, and substrate competitive phosphatidylinositol ether analog that potently and selectively inhibits Akt (PKB) (IC50 of 5.0 µM). Moderately inhibits PI 3-K activity (IC50 = 83.0 µM). Also inhibits the growth of various cancer cell lines with IC50 values in the 1 - 10 µM range.
Biological ActivityCell permeable: yes', 'Product competes with ATP.', 'Reversible: yes', 'Target IC50: 5.0 μM for Akt (PKB)
1L-6-hydroxymethyl-chiro-inositol 2-(R)-2-O-methyl-3-O-octadecylcarbonate Preparation Products And Raw materials
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