- 2,6-Dichloropyrazine
-
- $5.00/ KG
-
2026-03-03
- CAS:4774-14-5
- Min. Order: 1KG
- Purity: 99% hplc
- Supply Ability: 500TONS
- 2,6-Dichloropyrazine
-
- $99.00/ kg
-
2026-03-02
- CAS:4774-14-5
- Min. Order: 0.0010000000474974513kg
- Purity: 99%
- Supply Ability: 5000
- 2,6-Dichloropyrazine
-
- $10.00 / 1KG
-
2026-01-30
- CAS:4774-14-5
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 100 mt
|
| | 2,6-Dichloropyrazine Basic information |
| Product Name: | 2,6-Dichloropyrazine | | Synonyms: | 2,6-dichloro-pyrazin;Pyrazine, 2,6-dichloro-;2,6-Dichloropyrazine,99%;2,6-Dichlor-pyrazin;6-Dichloropyrazine;M-Dichloropyrazine;2,6-Dichloro-1,4-diazine;2,6-DICHLOROPYRAZINE | | CAS: | 4774-14-5 | | MF: | C4H2Cl2N2 | | MW: | 148.98 | | EINECS: | 225-316-8 | | Product Categories: | alkyl chloride;Building Blocks;Chemical Synthesis;Halogenated Heterocycles;Heterocyclic Building Blocks;Pesticides intermediate;Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;PyrazinesHeterocyclic Building Blocks;Heterocyclic Compounds;Pyrazines;Chloropyrazines, etc.;Heterocycles;Pyrazines, Pyrimidines & Pyridazines;API intermediates;Halides;Pyrazines, Pyrimidines & Pyridazines;bc0001 | | Mol File: | 4774-14-5.mol |  |
| | 2,6-Dichloropyrazine Chemical Properties |
| Melting point | 55-58 °C (lit.) | | Boiling point | 122 °C / 40mmHg | | density | 1.6445 (rough estimate) | | refractive index | 1.6300 (estimate) | | Fp | >230 °F | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | Soluble in ethanol and methanol. | | pka | -3.11±0.10(Predicted) | | form | Crystals or Crystalline Powder | | color | White to beige | | BRN | 2439 | | InChI | 1S/C4H2Cl2N2/c5-3-1-7-2-4(6)8-3/h1-2H | | InChIKey | LSEAAPGIZCDEEH-UHFFFAOYSA-N | | SMILES | Clc1cncc(Cl)n1 | | LogP | 1.530 | | CAS DataBase Reference | 4774-14-5(CAS DataBase Reference) | | NIST Chemistry Reference | 2,6-Dichloropyrazine(4774-14-5) | | EPA Substance Registry System | 2,6-Dichloropyrazine (4774-14-5) |
| Hazard Codes | Xi,Xn | | Risk Statements | 36/37/38-20/21/22 | | Safety Statements | 26-37/39-36/37/39-22-36 | | WGK Germany | 3 | | TSCA | TSCA listed | | HazardClass | IRRITANT | | HS Code | 29339990 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| | 2,6-Dichloropyrazine Usage And Synthesis |
| Chemical Properties | White Powder | | Uses | 2,6-Dichloropyrazine is used in the preparation of pyrazine and pyridine compounds as ATR kinase inhibitors. It is also used in the synthesis of oxacalixarenes containing nitrogen heterocycles. | | Synthesis | The production method of 2,6-dichloropyrazine comprises the following steps: carrying out ammoniation and cyclization reactions of raw materials comprising methyl chloroacetate, glyoxal and the like to prepare 2-hydroxypyrazine sodium, reacting 2-hydroxypyrazine sodium with phosphorous oxychloride under the catalysis action of N,N-dimethylaminopyridine to prepare 2-chloropyrazine, and chlorinating 2-chloropyrazine by chlorine under the catalysis action of triethylamine with dimethyl formamide as a solvent to prepare 2,6-dichloropyrazine. |
| | 2,6-Dichloropyrazine Preparation Products And Raw materials |
|