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| | Anti human tr-alpha Basic information |
| Product Name: | Anti human tr-alpha | | Synonyms: | Anti-THRA antibody produced in rabbit;Anti-THRA antibody produced in goat;Anti-THRA (176-190) antibody produced in rabbit;Anti-Thyroid Hormone Receptor α, N-Terminal antibody produced in rabbit;ANTI-THYROID HORMONE RECEPTOR ALPHA;ANTI-TR ALPHA;Anti-Nuclear receptor subfamily 1 group A member 1;Anti-c-erbA-1 | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![Anti human tr-alpha Structure]() |
| | Anti human tr-alpha Chemical Properties |
| storage temp. | -20°C | | form | buffered aqueous glycerol solution | | biological source | rabbit |
| WGK Germany | nwg | | Storage Class | 10 - Combustible liquids |
| | Anti human tr-alpha Usage And Synthesis |
| Uses | Anti-THRA antibody produced in rabbit, a Prestige Antibody, is developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org). Each antibody is tested by immunohistochemistry against hundreds of normal and disease tissues. These images can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. The antibodies are also tested using immunofluorescence and western blotting. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit . | | General Description | THRA (thyroid hormone receptor α) belongs to a family of nuclear receptors, which function as ligand-regulated transcription factors and are called thyroid hormone receptors (TRs). THRA is a predominant mammalian TR isoform. This receptor is highly expressed in central nervous system, myocardium, gastrointestinal tract and skeletal muscle. | | Biochem/physiol Actions | Conserved lysine in the DNA-binding domain of this receptor functions as a sensor of transcriptional regulation. This lysine is mutated in hepatocellular carcinoma (HCC). Mutations in this protein result in resistance to thyroid hormone, which is alleviated by thyroxine treatment. Population with rs939348 TT polymorphism in this gene show weak relation to increased risk to Alzheimer′s disease. This receptor is also up-regulated in patients with breast cancer. |
| | Anti human tr-alpha Preparation Products And Raw materials |
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