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| | 1,2-Distearoyl-3-dimethylammonium-propane Basic information |
| Product Name: | 1,2-Distearoyl-3-dimethylammonium-propane | | Synonyms: | 18:0 DAP;Octadecanoic acid, 1-[(dimethylamino)methyl]-1,2-ethanediyl ester;N,N,2-trimethyl-2-((octadecyloxy)methyl)henicosan-1-amine;3-(Dimethylamino)propane-1,2-diyl distearate;1,2-Distearoyl-3-dimethylammonium-propane | | CAS: | 121315-93-3 | | MF: | C41H81NO4 | | MW: | 652.09 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File |  |
| | 1,2-Distearoyl-3-dimethylammonium-propane Chemical Properties |
| Melting point | 37.5-38.5 °C | | Boiling point | 671.9±40.0 °C(Predicted) | | density | 0.905±0.06 g/cm3(Predicted) | | storage temp. | -20°C | | pka | 8.02±0.28(Predicted) | | form | powder | | InChI | 1S/C41H81NO4/c1-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-40(43)45-38-39(37-42(3)4)46-41(44)36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-2/h39H,5-38H2,1-4H3 | | InChIKey | RVBUSVJSKGVQQS-UHFFFAOYSA-N | | SMILES | [H]C(CN(C)C)(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O |
| WGK Germany | WGK 3 | | Storage Class | 11 - Combustible Solids |
| | 1,2-Distearoyl-3-dimethylammonium-propane Usage And Synthesis |
| Uses | 1,2-distearoyl-3-dimethylammonium-propane (18:0 DAP) might be used to formulate lipid nanoparticles (LNPs) and to test its efficiency of packaging mRNA into an LNP. It might also be used in the preparation of “bubble liposomes” (BLs). | | Biological Activity | 1,2-distearoyl-3-dimethylammonium-propane (18:0 DAP) is a cationic lipid and serves as a pH-sensitive transfection reagent. |
| | 1,2-Distearoyl-3-dimethylammonium-propane Preparation Products And Raw materials |
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