E3 Ligand-Linker Conjugate 6

Request For Quotation
E3 Ligand-Linker Conjugate 6 Suppliers list
Company Name: SuZhou Medinoah Co.,LTD.  
Tel: 0512-69561983 13914027025
Email: zhang_q@medinoah.com
Company Name: Jilin Province Woda Biotechnology Co., Ltd.  
Tel: 13504435624
Email: 1927928688@qq.com
Company Name: Shandong Territorial sea Biological Technology Co., LTD  
Tel: 15092083467
Email: tangfenjiushililiang@leadhigh.com.cn
Company Name: Molcoo Chemicals Inc.  
Tel: 18627923403
Email: 3001039764@qq.com
Company Name: Shenzhen Roark Pharma-Tec Co., Ltd.  
Tel: 13128912434
Email: 2880126944@qq.com
E3 Ligand-Linker Conjugate 6 Basic information
Product Name:E3 Ligand-Linker Conjugate 6
Synonyms:E3 Ligand-Linker Conjugate 6;Acetamide, N-(3-aminopropyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-;N-(3-aminopropyl)-2-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]oxy}acetamide;Pomadomide impurity 26
CAS:2022182-57-4
MF:C18H20N4O6
MW:388.37
EINECS:
Product Categories:
Mol File:2022182-57-4.mol
E3 Ligand-Linker Conjugate 6 Structure
E3 Ligand-Linker Conjugate 6 Chemical Properties
Boiling point 755.0±60.0 °C(Predicted)
density 1.431±0.06 g/cm3(Predicted)
pka10.68±0.40(Predicted)
Safety Information
MSDS Information
E3 Ligand-Linker Conjugate 6 Usage And Synthesis
UsesThalidomide-O-amido-C3-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.
IC 50Cereblon
References[1] Lohbeck J, et al. Practical synthesis of a phthalimide-based Cereblon ligand to enable PROTAC development. Bioorg Med Chem Lett. 2016 Nov 1;26(21):5260-5262. DOI:10.1016/j.bmcl.2016.09.048
E3 Ligand-Linker Conjugate 6 Preparation Products And Raw materials
Tag:E3 Ligand-Linker Conjugate 6(2022182-57-4) Related Product Information
N-(2-Trifluoromethyl-phenyl)-guanidine N-(3,4-Dimethoxy-phenyl)-guanidine N-(2-Methoxyethyl)urea INDEX NAME NOT YET ASSIGNED N-(3,4-dichlorophenyl)oxirane-2-carboxamide N-(1-((2-(1,1-dioxido-2,3-dihydrobenzo[f][1,4]thiazepin-4(5H)-yl)-6-methylquinazolin-4-yl)amino)-3-hydroxy-2-(hydroxymethyl)propan-2-yl)-2,2,2-trifluoroacetamide N-(2-Iodo-phenyl)-guanidine Cefazolin SodiuM iMpurity G Acetamide, N-(3-aminopropyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-, hydrochloride (1:1)