Tildacerfont manufacturers
- Tildacerfont
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- $193.00 / 5mg
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2026-03-05
- CAS:1014983-00-6
- Min. Order:
- Purity: 99.59%
- Supply Ability: 10g
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| | Tildacerfont Basic information |
| Product Name: | Tildacerfont | | Synonyms: | Tildacerfont;Pyrazolo[1,5-a]pyrimidine, 3-[4-chloro-2-(4-morpholinyl)-5-thiazolyl]-7-(1-ethylpropyl)-2,5-dimethyl-;4-(4-Chloro-5-(2,5-dimethyl-7-(pentan-3-yl)pyrazolo[1,5-a]pyrimidin-3-yl)thiazol-2-yl)morpholine;4-{4-chloro-5-[2,5-dimethyl-7-(pentan-3-yl)pyrazolo[1,5-a]pyrimidin-3-yl]-1,3-thiazol-2-yl}morpholine;Tildacerfont, 10 mM in DMSO | | CAS: | 1014983-00-6 | | MF: | C20H26ClN5OS | | MW: | 419.97 | | EINECS: | | | Product Categories: | | | Mol File: | 1014983-00-6.mol |  |
| | Tildacerfont Chemical Properties |
| density | 1.38±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | pka | 1.01±0.50(Predicted) | | form | Solid | | color | Light yellow to yellow | | InChI | InChI=1S/C20H26ClN5OS/c1-5-14(6-2)15-11-12(3)22-19-16(13(4)24-26(15)19)17-18(21)23-20(28-17)25-7-9-27-10-8-25/h11,14H,5-10H2,1-4H3 | | InChIKey | XVAWSBAQNIXMIO-UHFFFAOYSA-N | | SMILES | C12=C(C3SC(N4CCOCC4)=NC=3Cl)C(C)=NN1C(C(CC)CC)=CC(C)=N2 |
| | Tildacerfont Usage And Synthesis |
| Uses | Tildacerfont is a potent and orally active corticotrophin-releasing factor type 1 (CRF1) receptort antagonis. Tildacerfont effectively reduces adrenocorticotropic hormone (ACTH) and adrenal androgen levels. Tildacerfont has favourable safety profile. Tildacerfont can be used for researching congenital adrenal hyperplasia[1]. | | IC 50 | CRFR1 | | References | [1] Prete A, et al. Clinical advances in the pharmacotherapy of congenital adrenal hyperplasia. Eur J Endocrinol. 2021;186(1):R1-R14. Published 2021 Nov 30. DOI:10.1530/EJE-21-0794 |
| | Tildacerfont Preparation Products And Raw materials |
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