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| Product Name: | JAK1 ANTIBODY | | Synonyms: | JAK1 ANTIBODY;Rabbit Monoclonal JAK1 Antibody | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![JAK1 ANTIBODY Structure]() |
| | JAK1 ANTIBODY Chemical Properties |
| | JAK1 ANTIBODY Usage And Synthesis |
| Source | Rabbit | | Reactivity | Human;Mouse | | Background | Members of the Janus family of tyrosine kinases are activated by ligands binding to a number of associated cytokine receptors. Upon cytokine receptor activation, Jak proteins become autophosphorylated and phosphorylate their associated receptors to provide multiple binding sites for signaling proteins. These associated signaling proteins, such as Stats, Shc, insulin receptor substrates, and focal adhesion kinase, typically contain SH2 or other phospho-tyrosine-binding domains. | | References | [1] Leonard, W.J. and O'Shea, J.J. (1998) Annu Rev Immunol 16, 293-322.
[2] Darnell, J.E. (1997) Science 277, 1630-5.
[3] VanderKuur, J. et al. (1995) J Biol Chem 270, 7587-93.
[4] Argetsinger, L.S. et al. (1995) J Biol Chem 270, 14685-92.
[5] Zhu, T. et al. (1998) J Biol Chem 273, 10682-9. |
| | JAK1 ANTIBODY Preparation Products And Raw materials |
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