| Company Name: |
BOC Sciences
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16314854226 |
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info@bocsci.com |
| Products Intro: |
Product Name:3-Hydroxy darifenacin
CAS:206048-82-0
Purity:95% Package:1G;10G;100G Remarks:3-Hydroxy darifenacin is a metabolite of darifenacin.
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| Company Name: |
Shanghai Hongye Biotechnology Co. Ltd
|
| Tel: |
400-9205774 |
| Email: |
sales@glpbio.cn |
| Products Intro: |
Product Name:3-hydroxy Darifenacin
CAS:206048-82-0
Purity:>98% Package:1mg;10mg;50mg;100mg;
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Darifenacin 3-Hydroxy Impurity manufacturers
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| | Darifenacin 3-Hydroxy Impurity Basic information |
| Product Name: | Darifenacin 3-Hydroxy Impurity | | Synonyms: | Darifenacin 3-Hydroxy Impurity;3-Pyrrolidineacetamide, 1-[2-(2,3-dihydro-3-hydroxy-5-benzofuranyl)ethyl]-α,α-diphenyl-, (3S)-;(3S)-1-[2-(2,3-dihydro-3-hydroxy-5-benzofuranyl)ethyl]-α,α-diphenyl-3-pyrrolidineacetamide | | CAS: | 206048-82-0 | | MF: | C28H30N2O3 | | MW: | 442.56 | | EINECS: | | | Product Categories: | | | Mol File: | 206048-82-0.mol |  |
| | Darifenacin 3-Hydroxy Impurity Chemical Properties |
| Boiling point | 644.1±55.0 °C(Predicted) | | density | 1.247±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO: soluble; Methanol: soluble | | form | A solid | | pka | 13.52±0.20(Predicted) |
| | Darifenacin 3-Hydroxy Impurity Usage And Synthesis |
| Description | 3-hydroxy Darifenacin is a metabolite of darifenacin . It is an antagonist of M1-5 muscarinic receptors (Kis = 17.78, 79.43, 2.24, 36.31, and 6.17 nM, respectively, in CHO cells). | | Uses | 3-Hydroxy darifenacin is a metabolite of Darifenacin (HY-A0033). 3-Hydroxy darifenacin is an antagonist of M1-5 muscarinic receptors with Kis values of 17.78, 79.43, 2.24, 36.31 and 6.17 nM, respectively in CHO cells[1]. | | References | [1] Mansfield KJ, et al. Comparison of receptor binding characteristics of commonly used muscarinic antagonists in human bladder detrusor and mucosa. J Pharmacol Exp Ther. 2009 Mar;328(3):893-9. DOI:10.1124/jpet.108.145508 |
| | Darifenacin 3-Hydroxy Impurity Preparation Products And Raw materials |
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