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IIIM-290
(IIIM290) manufacturers
- IIIM-290
-
- $3400.00
-
2026-07-27
- CAS:2213468-64-3
- Purity:
- Supply Ability: 10g
- IIIM-290
-
- $3400.00
-
2026-07-27
- CAS:2213468-64-3
- Purity:
- Supply Ability: 10g
- IIIM-290
-
- $3400.00
-
2025-08-22
- CAS:2213468-64-3
- Purity:
- Supply Ability: 10g
|
| | IIIM-290
(IIIM290) Basic information |
| Product Name: | IIIM-290
(IIIM290) | | Synonyms: | IIIM-290
(IIIM290);4H-1-Benzopyran-4-one, 2-[2-(2,6-dichlorophenyl)ethenyl]-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methyl-4-piperidinyl]- | | CAS: | 2213468-64-3 | | MF: | C23H21Cl2NO5 | | MW: | 462.32 | | EINECS: | | | Product Categories: | | | Mol File: | 2213468-64-3.mol |  |
| | IIIM-290
(IIIM290) Chemical Properties |
| | IIIM-290
(IIIM290) Usage And Synthesis |
| Uses | IIIM-290 is a potent and oral CDK inhibitor with IC50s of 90 and 94 nM for CDK2/A and CDK9/T1. | | IC 50 | CDK2/A: 90 nM (IC50); CDK9/T1: 94 nM (IC50) | | References | [1] Bharate SB, et al. Discovery and Preclinical Development of IIIM-290, an Orally Active Potent Cyclin-Dependent Kinase Inhibitor. J Med Chem. 2018 Feb 22;61(4):1664-1687. DOI:10.1021/acs.jmedchem.7b01765 |
| | IIIM-290
(IIIM290) Preparation Products And Raw materials |
|