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| | m-PEG5-nitrile Basic information |
| | m-PEG5-nitrile Chemical Properties |
| Boiling point | 366.2±32.0 °C(Predicted) | | density | 1.037±0.06 g/cm3(Predicted) |
| | m-PEG5-nitrile Usage And Synthesis |
| Description | m-PEG5-nitrile is a PEG linker containing a nitrile terminal group. The nitrile group can undergo hydrolysis, reduction and other reactions. The hydrophilic PEG spacer increases the solubility of compounds in aqueous media. | | Uses | m-PEG5-nitrile is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. | | References | [1] Saifer MG, et al. Selectivity of binding of PEGs and PEG-like oligomers to anti-PEG antibodies induced by methoxyPEG-proteins. Mol Immunol. 2014 Feb;57(2):236-46. DOI:10.1016/j.molimm.2013.07.014 |
| | m-PEG5-nitrile Preparation Products And Raw materials |
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