rel-(2R,3R,4S)-4-(1,3-Benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)-3-pyrrolidinecarboxylic acid

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rel-(2R,3R,4S)-4-(1,3-Benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)-3-pyrrolidinecarboxylic acid Suppliers list
Company Name: TargetMol Chemicals Inc.
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Products Intro: Product Name:A 127722；A-127722;A127722
CAS:195704-72-4
Package:10 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
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Products Intro: Product Name:A 127722
CAS:195704-72-4
Purity:>=98%(HPLC) Package:$1099.9/10mg;Bulk package Remarks:98%(HPLC)
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Products Intro: Product Name:A 127722
CAS:195704-72-4
Purity:>98% Package:1mg;10mg;50mg;100mg;
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Products Intro: Product Name:A 127722
CAS:195704-72-4
Purity:>=98% by HPLC Remarks:Reach out to us for more information about custom solutions.
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Products Intro: CAS:195704-72-4
Purity:99% HPLC Package:10mg;25mg;50mg;100mg;500mg
rel-(2R,3R,4S)-4-(1,3-Benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)-3-pyrrolidinecarboxylic acid Basic information
Product Name:rel-(2R,3R,4S)-4-(1,3-Benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)-3-pyrrolidinecarboxylic acid
Synonyms:rel-(2R,3R,4S)-4-(1,3-Benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)-3-pyrrolidinecarboxylic acid;3-Pyrrolidinecarboxylic acid, 4-(1,3-benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)-, (2R,3R,4S)-rel-;A 127722
CAS:195704-72-4
MF:C29H38N2O6
MW:510.62
EINECS:
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Mol File:195704-72-4.mol
rel-(2R,3R,4S)-4-(1,3-Benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)-3-pyrrolidinecarboxylic acid Structure
rel-(2R,3R,4S)-4-(1,3-Benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)-3-pyrrolidinecarboxylic acid Chemical Properties
storage temp. Store at -20°C
solubility Soluble in DMSO
Safety Information
MSDS Information
rel-(2R,3R,4S)-4-(1,3-Benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)-3-pyrrolidinecarboxylic acid Usage And Synthesis
UsesA-127722 is A 2, 4-dialarylpyrrolidine-3-carboxylic acid ETA selective endothelin receptor (ET receptor) antagonist with IC50 value of 0.36 nM[1].
DefinitionChEBI: Atrasentan is a member of pyrrolidines.
storageStore at -20°C
References[1] Winn M, et al. 2,4-Diarylpyrrolidine-3-carboxylic acids--potent ETA selective endothelin receptor antagonists. 1. Discovery of A-127722. J Med Chem. 1996 Mar 1;39(5):1039-48. DOI:10.1021/jm9505369
rel-(2R,3R,4S)-4-(1,3-Benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)-3-pyrrolidinecarboxylic acid Preparation Products And Raw materials
Tag:rel-(2R,3R,4S)-4-(1,3-Benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)-3-pyrrolidinecarboxylic acid(195704-72-4) Related Product Information