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| | Uridine 5'-diphosphoglucose disodium salt from Saccharomyces cerevisiae Basic information |
| Product Name: | Uridine 5'-diphosphoglucose disodium salt from Saccharomyces cerevisiae | | Synonyms: | UDP-glc, Uridine-diphosphate-glucose disodium salt, Uridine[5]diphospho[1]-α-D-glucopyranose disodium salt;UDP-Glc, UDPG;Uridine 5'-(trihydrogen diphosphate) mono-α-D-glucopyranosye ester disodium salt;disodium [[(2R,3S,4R,5R)-5-(2,4-diketopyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-oxido-phosphoryl] [(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-methylol-tetrahydropyran-2-yl] phosphate;disodium [[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-oxidanidyl-phosphoryl] [(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] phosphate;disodium [[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] [(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] phosphate;Uridine 5′-diphosphoglucose disodium salt from Saccharomyces cerevisiae,UDP-Glc, UDPG;Uridine-5''-diphospho-D-glucose disodium salt | | CAS: | 28053-08-9 | | MF: | C15H25N2NaO17P2 | | MW: | 590.3 | | EINECS: | 248-801-6 | | Product Categories: | Bases & Related Reagents;Carbohydrates & Derivatives;Heterocycles;Intermediates & Fine Chemicals;Nucleotides;Pharmaceuticals | | Mol File: | 28053-08-9.mol |  |
| | Uridine 5'-diphosphoglucose disodium salt from Saccharomyces cerevisiae Chemical Properties |
| Melting point | >162°C (dec.) | | storage temp. | -20°C | | solubility | H2O: soluble50mg/mL, clear | | form | Solid | | color | White to Off-White | | biological source | Saccharomyces cerevisiae | | Water Solubility | H2O: 50mg/mL, clear | | BRN | 4290380 | | Stability: | Hygroscopic | | InChIKey | PKJQEQVCYGYYMM-XXXBXXKPSA-L | | SMILES | O[C@@H]1[C@@H]([C@@H](COP(O)(=O)OP(O)(=O)O[C@@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)O)O[C@H]1N1C=CC(=O)NC1=O)O.[NaH] |&1:1,2,3,14,15,16,18,20,26,r| |
| Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | HS Code | 29400090 | | Storage Class | 11 - Combustible Solids |
| | Uridine 5'-diphosphoglucose disodium salt from Saccharomyces cerevisiae Usage And Synthesis |
| Description | Uridine 5'-diphosphoglucose disodium salt, secreted by
cardiomyocytes during ischemia and reperfu, is a potent agonist of the
proinflammatory P2Y14 receptor. It acts an important role in the
regulation of inflammation and neutrophil polarization in neutrophils.
Uridine 5’-diphosphoglucose disodium salt is also the precursor of
glucose-containing oligosaccharides, polysaccharides, glycoproteins, and glycolipids in animal tissues and in some microorganisms.
Uridine 5’-diphosphoglucose disodium salt is promising for research in
counteracting myocardial infarction/reperfusion (MIR)-induced
inflammation in the heart tissue. | | Uses | Uridine 5'-diphosphoglucose disodium salt is a phosphorylated uridine derivative used in nucleotide sugars metabolism as an activated form of glucose as a substrate for the enzyme glucosyltransferases. It is used in the treatment of chronic alco holism. It is used in characterization of limonoid glucosyltransferase. | | Uses | Glc transferase substrate | | Uses | Disodium UDP-glucose is a phosphorylated uridine derivative used in nucleotide sugars metabolism as an activated form of glucose as a substrate for the enzyme glucosyltransferases. It is used in the treatment of chronic alcoholism. It is used in characterization of limonoid glucosyltransferase. | | Application | Uridine 5'-diphosphoglucose disodium salt is a key component of metabolism. As the "activated" form of glucose, it directly participates in a variety of biochemical reactions. "Disodium salt" refers to its stable, water-soluble form in the laboratory, where two sodium ions (Na+) balance the molecule's charge. UDP-G is the primary glucose donor for building energy reserves (glycogen), structural components in plants, and converting glucose into other essential sugars (such as galactose), while also playing a crucial role in detoxification. | | General Description | Uridine diphosphate glucose (UDP-glucose) is a glycogen precursor. The transfer of glucose from UDP-glucose to growing glycogen chain is catalyzed by the enzyme glycogen synthase. The enzyme uridine diphosphate galactose-4-epimerase catalyzes the formation of UDP-glucose from UDP-galactose. | | Biochem/physiol Actions | Uridine diphosphate glucose (UDP-glucose) is an essential mediator of the cellular metabolic pathways. In yeast, the high levels of trehalose and glycogen favor increased levels of UDP-glucose. |
| | Uridine 5'-diphosphoglucose disodium salt from Saccharomyces cerevisiae Preparation Products And Raw materials |
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