| Company Name: |
Shanghai Hongye Biotechnology Co. Ltd
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| Tel: |
400-9205774 |
| Email: |
sales@glpbio.cn |
| Products Intro: |
Product Name:Leukotriene D4 methyl ester
Purity:>98% Package:1mg;10mg;50mg;100mg;
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| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
|
| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:Leukotriene D4 methyl ester
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
|
| Company Name: |
MedBioPharmaceutical Technology Inc
|
| Tel: |
021-69568360 18916172912 |
| Email: |
order@med-bio.cn |
| Products Intro: |
Product Name:LEUKOTRIENE D4 METHYL ESTER
CAS:103476-23-9
Purity:98% Package:50μg;25μg;100μg Remarks:Medbio
|
| Company Name: |
Cayman Chemical Company
|
| Tel: |
800-364-9897 |
| Email: |
sales@caymanchem.com |
| Products Intro: |
Product Name:Leukotriene D4 methyl ester
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| | LEUKOTRIENE D4 METHYL ESTER Basic information |
| Product Name: | LEUKOTRIENE D4 METHYL ESTER | | Synonyms: | Reaxys ID: 5181548;LEUKOTRIENE D4 METHYL ESTER;Glycine, S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-1-hydroxy-5-methoxy-5-oxopentyl]-2,4,6,9-pentadecatetraenyl]-L-cysteinyl- (9CI) | | CAS: | 103476-23-9 | | MF: | C26H42N2O6S | | MW: | 510.69 | | EINECS: | | | Product Categories: | | | Mol File: | 103476-23-9.mol |  |
| | LEUKOTRIENE D4 METHYL ESTER Chemical Properties |
| storage temp. | -20°C | | solubility | DMF: 20 mg/ml
DMSO: 20 mg/ml
Ethanol: 1 mg/mlPBS (pH 7.2): .15 mg/ml |
| | LEUKOTRIENE D4 METHYL ESTER Usage And Synthesis |
| Description | Leukotriene D4 (LTD4) is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A) produced by the metabolism of LTC4 by γ-glutamyl transpeptidase.1,2 LTD4-induced bronchoconstriction and enhanced vascular permeability contribute to the pathogenesis of asthma and acute hypersensitivity.3,4 LTD4 is several hundred fold more potent than LTC4 at the cysteinyl-leukotriene 1 (CysLT1) receptor, but they exhibit approximately equal affinity at the CysLT2 receptor.5,6 LTD4 methyl ester is a more lipid soluble form of LTD4. The biological activity of LTD4 methyl ester has not been reported.WARNING This product is not for human or veterinary use. | | References | [1] L ORNING B S S Hammarström. Leukotriene D: a slow reacting substance from rat basophilic leukemia cells.[J]. Proceedings of the National Academy of Sciences of the United States of America, 1980, 77 4: 2014-2017. DOI: 10.1073/pnas.77.4.2014
[2] S HAMMARSTRÖM K B L Orning. Metabolism of leukotrienes.[J]. Molecular and Cellular Biochemistry, 1985, 69 1: 7-16. DOI: 10.1007/bf00225922
[3] PER HEDQVIST. Biological profile of Ieukotrienes C4 and D4[J]. Acta Physiologica, 1980, 110 3: 331-333. DOI: 10.1111/j.1748-1716.1980.tb06676.x
[4] BENGT SAMUELSSON. Leukotrienes and Lipoxins: Structures, Biosynthesis, and Biological Effects[J]. Science, 1987, 237 4819. DOI: 10.1126/science.2820055
[5] KEVIN R. LYNCH. Characterization of the human cysteinyl leukotriene CysLT1 receptor[J]. Nature, 1999, 399 6738: 789-793. DOI: 10.1038/21658
[6] C E HEISE. Characterization of the human cysteinyl leukotriene 2 receptor.[J]. The Journal of Biological Chemistry, 2000, 275 39: 30531-30536. DOI: 10.1074/jbc.m003490200 |
| | LEUKOTRIENE D4 METHYL ESTER Preparation Products And Raw materials |
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