(S)-((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochloride

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(S)-((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochloride manufacturers

(S)-((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochloride Basic information

Product Name:	(S)-((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochloride
Synonyms:	Famotidine EP Impurity H DiHCl;Famotidine Impurity H DiHCl;N-[4-[[(amino iminomethyl) thio]-methyl]-2-thiazolyl]-guanidine dihydrochloride (FMT-II);Carbamimidothioic acid [2-[(aminoiminomethyl)amino]-4-thiazolyl]methyl ester dihydrochloride;N-(4-(((AMINOIMINOMETHYL)THIO)METHYL)-2-THIAZOLYL)GUANIDINE;S-[(2-Guanidino-4-thiazolyl)methyl]isothiourea 2HCl;S-[(2-Guanidino-4-thiazolyl)methyl]isothiourea dihydrochloride;N-[4-(Aminoiminomethyl)Thiomethyl-2-Thiazolyl]Guanidine Dihydrochloride
CAS:	88046-01-9
MF:	C6H11ClN6S2
MW:	266.77
EINECS:	618-106-6
Product Categories:	Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds
Mol File:	88046-01-9.mol

(S)-((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochloride Chemical Properties

Melting point	>188oC (dec.)
storage temp.	Refrigerator
solubility	DMSO (Sparingly), Methanol (Slightly)
form	Solid
color	White to Off-White
PH	3.89 at 1000g/L
InChI	InChI=1S/C6H10N6S2.ClH/c7-4(8)12-6-11-3(2-14-6)1-13-5(9)10;/h2H,1H2,(H3,9,10)(H4,7,8,11,12);1H
InChIKey	DMXJVYCDETXZRR-UHFFFAOYSA-N
SMILES	N(C1SC=C(CSC(N)=N)N=1)C(N)=N.Cl
LogP	1 at 30℃ and pH3.89

Safety Information

MSDS Information

(S)-((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochloride Usage And Synthesis

Chemical Properties	Beige crystals, melting point 215-216°C (189-191.5°C).
Uses	Famotidine intermediate.
Definition	Famotidine EP Impurity H is chemically (S)-((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochloride. It is also known as Famotidine Isothiourea Impurity . Famotidine EP Impurity H can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Famotidine.

(S)-((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochloride Preparation Products And Raw materials

Tag:(S)-((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochloride(88046-01-9) Related Product Information

N-DesaMinosulfonyl-N-cyano FaMotidine Famotidine EP Impurity A 2-Methyl-4-isothiazolin-3-one Benzothiazole Methanol Methyl acrylate Methylparaben Tetramethylthiourea 3-[2-(Diaminomethyleneamino)-1,3-thiazol-4-ylmethylsulphinyl]-N-sulphamoyl propanamide FAMOTIDINE RELATED COMPOUND B Sulfamide [3-[[[2-(DiaMinoMethyleneaMino)-4-thiazolyl]Methyl]thio]propionyl]sulfaMide Hydrochloride (FaMotidine IMpurity) Methylchloroisothiazolinone/methylisothiazolinone mixture (MCIT/MIT) Acetonitrile Glycine Thiosemicarbazide 2-(4-(Chloromethyl)thiazol-2-yl)guanidine Bis[(2-guanidino-4-thiazolyl)methyl]disulfide