| Company Name: |
BOC Sciences |
| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
PNZ5 manufacturers
- PNZ5
-
- $98.00
-
2026-05-11
- CAS:1629277-36-6
- Purity: 99.61%
- Supply Ability: 10g
- PNZ5
-
- $98.00
-
2026-05-11
- CAS:1629277-36-6
- Purity: 99.61%
- Supply Ability: 10g
|
| Product Name: | PNZ5 | | Synonyms: | PNZ5;1H-Isoindol-1-one, 5-(3,5-dimethyl-4-isoxazolyl)-2,3-dihydro-2-methyl-3-phenyl-, (3S)-;PNZ5,PNZ-5;PNZ5, 10 mM in DMSO | | CAS: | 1629277-36-6 | | MF: | C20H18N2O2 | | MW: | 318.37 | | EINECS: | | | Product Categories: | | | Mol File: | 1629277-36-6.mol |  |
| storage temp. | Store at -20°C | | solubility | Soluble in DMSO |
| Description | PNZ5 is a potent and isoxazole-based pan-BET inhibitor with high selectivity and potency similar to the well-established (+)-JQ1, with a KD of 5.43 nM for BRD4(1)[1].
BRD4(1)|5.43 nM (Kd)
| | Uses | PNZ5 is a potent and isoxazole-based pan-BET inhibitor with high selectivity and potency similar to the well-established (+)-JQ1, with a KD of 5.43 nM for BRD4(1)[1]. | | IC 50 | BRD4(1): 5.43 nM (Kd) | | References | [1]. Montenegro RC, et al. BET inhibition as a new strategy for the treatment of gastric cancer. Oncotarget. 2016 Jul 12;7(28):43997-44012. |
| | PNZ5 Preparation Products And Raw materials |
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