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| Product Name: | ANXA1 Antibody | | Synonyms: | ANXA1 Antibody;Mouse Monoclonal ANXA1 Antibody | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![ANXA1 Antibody Structure]() |
| | ANXA1 Antibody Chemical Properties |
| | ANXA1 Antibody Usage And Synthesis |
| Applications | The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. | | Immunogen | Anti-human ANXA1 mAb, clone PAT2G5AT, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human ANXA1 protein 1-346 amino acids purified from E. coli.
| | Background | ANXA1 is part of the family of Ca(2+)-dependent phospholipid binding proteins which have a Mw between 35kDa-40kDa and are situated on the cytosolic face of the plasma membrane. ANXA1 protein has a Mw of 40kDa, with phospholipase A2 inhibitory activity to bind from two to four calcium ions with high affinity. Since phospholipase A2 is necessary for the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes, ANXA1 might have potential anti-inflammatory activity. ANXA1 promotes membrane fusion and iplays a role in exocytosis. The recognition of ANXA1 protein by immunocytochemical leads a simple, highly sensitive and specific assay for diagnosis of hairy cell leukemia. |
| | ANXA1 Antibody Preparation Products And Raw materials |
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