| Company Name: |
Absin Bioscience Inc.
|
| Tel: |
021-38015121 18438616290 |
| Email: |
lanwu@univ-bio.com |
| Products Intro: |
Product Name:CYP17A1 antibody
Package:50ul Remarks: 见爱必信官网
|
| Company Name: |
Hubei Ipodix Biotechnology Co.,Ltd.
|
| Tel: |
18007124176 19384116026 |
| Email: |
2706668885@qq.com |
| Products Intro: |
Product Name:CYP17A1 antibody
Purity:99% Package:50ul/RMB 1280;100ul/RMB 2180
|
| Company Name: |
CUSABIO TECHNOLOGY LLC
|
| Tel: |
027-87196173 |
| Email: |
cusabio@163.com |
| Products Intro: |
Product Name:CYP17A1 Antibody
|
| Company Name: |
Hubei Serenity BioSolutions Co., Ltd.
|
| Tel: |
027-19371278702 18008634902 |
| Email: |
19384116026@163.com |
| Products Intro: |
Product Name:Rabbit Polyclonal CYP17A1 Antibody
Package:20μl;50μl;100μl
|
| Company Name: |
GeneTex, Inc.
|
| Tel: |
0755-26755892 1-949-553-1900 |
| Email: |
international@genetex.com |
| Products Intro: |
Product Name:CYP17A1 antibody
|
|
| Product Name: | CYP17A1 antibody | | Synonyms: | CYP17A1 antibody;Rabbit Polyclonal CYP17A1 Antibody | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![CYP17A1 antibody Structure]() |
| | CYP17A1 antibody Chemical Properties |
| | CYP17A1 antibody Usage And Synthesis |
| Source | Rabbit | | Reactivity | Human | | Background | CYP17A1, also known as cytochrome P450C17, is a steroidogenic enzyme belonging to the P450 cytochrome superfamily of monooxygenases. In humans, CYP17A1 expression is abundantly expressed in the adrenal cortex, where it plays a central role in the androgen synthesis pathway. CYP17A1 is the primary target of abiraterone, a synthetic steroid used in the treatment of castration-resistant prostate cancer. Abiraterone is converted to the more active form D4A, which antagonizes androgen receptor signaling by inhibiting CYP17A1 and other steroidogenic enzymes. This suppresses the synthesis of 5α-dihydrotestosterone, which is a driver of castration-resistant prostate cancer cell growth. | | References | [1] Missaghian, E. et al. (2009) J Endocrinol 202, 99-109.
[2] Tee, M.K. and Miller, W.L. (2013) J Biol Chem 288, 23903-13.
[3] Li, Z. et al. (2015) Nature 523, 347-51.
[4] Thoma, C. (2015) Nat Rev Urol 12, 363. |
| | CYP17A1 antibody Preparation Products And Raw materials |
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