| Company Name: |
Shanghai Aladdin Biochemical Technology Co.,Ltd.
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| Tel: |
400-6206333 13167063860 |
| Email: |
anhua.mao@aladdin-e.com |
| Products Intro: |
Product Name:MGMT Antibody
Purity:无载体, ExactAb?, 无叠氮钠, 已验证, 见COA Package:10μl/RMB 499.90;50μl/RMB 1299.90;100μl/RMB 2099.90
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| Company Name: |
Hubei Ipodix Biotechnology Co.,Ltd.
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| Tel: |
18007124176 19384116026 |
| Email: |
2706668885@qq.com |
| Products Intro: |
Product Name:MGMT antibody
Purity:99% Package:50ul/RMB 1280;100ul/RMB 2180
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| Company Name: |
Novus Biologicals
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| Tel: |
400821347 |
| Email: |
orders@novusbio.com |
| Products Intro: |
Product Name:MGMT Antibody
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| Company Name: |
CUSABIO TECHNOLOGY LLC
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| Tel: |
027-87196173 |
| Email: |
cusabio@163.com |
| Products Intro: |
Product Name:MGMT Antibody
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| | MGMT antibody Chemical Properties |
| | MGMT antibody Usage And Synthesis |
| Source | Rabbit | | Reactivity | Human;Monkey | | Background | MGMT is a DNA repair enzyme that participates in a suicide reaction that specifically removes methyl or alkyl groups from the O(6) position of guanine, restoring guanine to its normal form without causing DNA breaks. MGMT protects cells from alkylating toxins, and is an important factor in drug resistance to alkylating therapeutic agents. It is ubiquitously expressed in normal human tissues and is overexpressed in many types of human tumors, but epigenetically silenced in other tumors. MGMT silencing is a marker associated with poor prognosis, but is a good predictive marker for response to alkylating agent chemotherapy. | | References | [1] Pegg, A.E. (2000) Mutat. Res. 462, 83-100.
[2] Bobola, M.S. et al. (2005) Clin. Cancer Res. 11, 2747-2755.
[3] Pollack, I.F. et al. (2006) J. Clin. Oncol. 24, 3431-3437.
[4] Gerson, S.L. et al. (1986) Carcinogenesis 7, 745-749.
[5] Soejima, H. et al. (2005) Biochem. Cell Biol. 83, 429-437. |
| | MGMT antibody Preparation Products And Raw materials |
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