2-Propenamide, N-[2-[[2-(dimethylamino)ethyl]methylamino]-4-methoxy-5-[[4-(5-methoxy-1H-pyrrolo[3,2-b]pyridin-1-yl)-2-pyrimidinyl]amino]phenyl]-

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2-Propenamide, N-[2-[[2-(dimethylamino)ethyl]methylamino]-4-methoxy-5-[[4-(5-methoxy-1H-pyrrolo[3,2-b]pyridin-1-yl)-2-pyrimidinyl]amino]phenyl]- Suppliers list
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2-Propenamide, N-[2-[[2-(dimethylamino)ethyl]methylamino]-4-methoxy-5-[[4-(5-methoxy-1H-pyrrolo[3,2-b]pyridin-1-yl)-2-pyrimidinyl]amino]phenyl]- manufacturers

  • BEBT-109
  • BEBT-109 pictures
  • $459.00
  • 2026-07-27
  • CAS:2050906-40-4
  • Purity: 97.26%
  • Supply Ability: 10g
2-Propenamide, N-[2-[[2-(dimethylamino)ethyl]methylamino]-4-methoxy-5-[[4-(5-methoxy-1H-pyrrolo[3,2-b]pyridin-1-yl)-2-pyrimidinyl]amino]phenyl]- Basic information
Product Name:2-Propenamide, N-[2-[[2-(dimethylamino)ethyl]methylamino]-4-methoxy-5-[[4-(5-methoxy-1H-pyrrolo[3,2-b]pyridin-1-yl)-2-pyrimidinyl]amino]phenyl]-
Synonyms:2-Propenamide, N-[2-[[2-(dimethylamino)ethyl]methylamino]-4-methoxy-5-[[4-(5-methoxy-1H-pyrrolo[3,2-b]pyridin-1-yl)-2-pyrimidinyl]amino]phenyl]-;BEBT-109
CAS:2050906-40-4
MF:C27H32N8O3
MW:516.59
EINECS:
Product Categories:
Mol File:2050906-40-4.mol
2-Propenamide, N-[2-[[2-(dimethylamino)ethyl]methylamino]-4-methoxy-5-[[4-(5-methoxy-1H-pyrrolo[3,2-b]pyridin-1-yl)-2-pyrimidinyl]amino]phenyl]- Structure
2-Propenamide, N-[2-[[2-(dimethylamino)ethyl]methylamino]-4-methoxy-5-[[4-(5-methoxy-1H-pyrrolo[3,2-b]pyridin-1-yl)-2-pyrimidinyl]amino]phenyl]- Chemical Properties
density 1.24±0.1 g/cm3(Predicted)
form Solid
pka12.65±0.70(Predicted)
color White to off-white
Safety Information
MSDS Information
2-Propenamide, N-[2-[[2-(dimethylamino)ethyl]methylamino]-4-methoxy-5-[[4-(5-methoxy-1H-pyrrolo[3,2-b]pyridin-1-yl)-2-pyrimidinyl]amino]phenyl]- Usage And Synthesis
UsesBEBT-109 is a potent pan-mutant-selective EGFR inhibitor. BEBT-109 has improved pharmacokinetic properties. BEBT-109 can be used for multiple mutant-EGFR-driven non-small cell lung cancer (NSCLC) research[1].
References[1] Fan F, et al BEBT-109, a pan-mutant-selective EGFR inhibitor with potent antitumor activity in EGFR-mutant non-small cell lung cancer. Transl Oncol. 2021 Feb;14(2):100961. DOI:10.1016/j.tranon.2020.100961
2-Propenamide, N-[2-[[2-(dimethylamino)ethyl]methylamino]-4-methoxy-5-[[4-(5-methoxy-1H-pyrrolo[3,2-b]pyridin-1-yl)-2-pyrimidinyl]amino]phenyl]- Preparation Products And Raw materials
Tag:2-Propenamide, N-[2-[[2-(dimethylamino)ethyl]methylamino]-4-methoxy-5-[[4-(5-methoxy-1H-pyrrolo[3,2-b]pyridin-1-yl)-2-pyrimidinyl]amino]phenyl]-(2050906-40-4) Related Product Information
EGFR Protein, HUMAN (621A.A, HEK293, FC) EGFR protein, HUMAN (BIOTINYLATED, HEK293, HIS-AVI) HER2/CD340 protein, HUMAN (BIOTINYLATED, HEK293, HIS) HER3 Protein, HUMAN (BIOTINYLATED, HEK293, HIS-AVI) HER2/CD340 Protein, RAT (HEK293) EGFR Protein, HUMAN (HEK293, HIS-AVI)