QTX125 manufacturers
- QTX125
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- $1520.00
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2026-05-11
- CAS:1279698-31-5
- Purity:
- Supply Ability: 10g
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| Product Name: | QTX125 | | Synonyms: | QTX125;1H-Pyrrole-2-carboxamide, 3-(3-furanyl)-N-[[4-[(hydroxyamino)carbonyl]phenyl]methyl]-5-(4-hydroxyphenyl)-;QTX125,QTX-125 | | CAS: | 1279698-31-5 | | MF: | C23H19N3O5 | | MW: | 417.41 | | EINECS: | | | Product Categories: | | | Mol File: | 1279698-31-5.mol |  |
| | QTX125 Chemical Properties |
| density | 1.382±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | pka | 8.88±0.10(Predicted) |
| | QTX125 Usage And Synthesis |
| Uses | QTX125 is a potent and highly selective HDAC6 inhibitor. QTX125 exhibits excellent selectivity over other HDACs. QTX125 has antitumor effects[1]. | | in vivo | QTX125 (60 mg/kg; i.p.; daily dosing for 5 days; for 4 weeks) treatment inhibits tumor growth in REC-1 or MINO cells xenografted in nude mice[1]. | Animal Model: | Nude mice bearing REC-1 or MINO cells[1] | | Dosage: | 60 mg/kg
| | Administration: | Intraperitoneal administration; daily dosing for 5 days; for 4 weeks | | Result: | Inhibited tumor growth in REC-1 or MINO cells xenografted in nude mice. |
| | IC 50 | HDAC6 | | References | [1] Montserrat Pérez-Salvia, et al. In vitro and in vivo activity of a new small-molecule inhibitor of HDAC6 in mantle cell lymphoma. Haematologica. 2018 Nov;103(11):e537-e540. DOI:10.3324/haematol.2018.189241 |
| | QTX125 Preparation Products And Raw materials |
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