N-[[P(S),2''R]-2''-deoxy-3''-O-[(1,1-dimethylethyl)dimethylsilyl]-2''-fluoro-2''-methyl-P-phenyl-5''-uridylyl]-L-alanine 1-Methylethyl Ester

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N-[[P(S),2''R]-2''-deoxy-3''-O-[(1,1-dimethylethyl)dimethylsilyl]-2''-fluoro-2''-methyl-P-phenyl-5''-uridylyl]-L-alanine 1-Methylethyl Ester Suppliers list
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Products Intro: Product Name:N-[[P(S),2’R]-2’-deoxy-3’-O-[(1,1-dimethylethyl)dimethylsilyl]-2’-fluoro-2’-methyl-P-phenyl-5’-uridylyl]-L-alanine1-MethylethylEster
CAS:1256490-54-6
Purity:NULL Package:10mg;2.5mg;25mg;5mg Remarks:NULL
Company Name: United States Biological  
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Products Intro: Product Name:N-[[P (S) , 2'R]-2'-deoxy-3'-O-[ (1, 1-dimethylethyl) dimethylsilyl]-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-L-alanine 1-Methylethyl Ester
CAS:1256490-54-6
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Products Intro: Product Name:N-[[P(S),2'R]-2'-deoxy-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-L-alanine 1-Methylethyl Ester
CAS:1256490-54-6
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Products Intro: Product Name:N-[[P(S),2''R]-2''-deoxy-3''-O-[(1,1-dimethylethyl)dimethylsilyl]-2''-fluoro-2''-methyl-P-phenyl-5''-uridylyl]-L-alanine 1-Methylethyl Ester
CAS:1256490-54-6
N-[[P(S),2''R]-2''-deoxy-3''-O-[(1,1-dimethylethyl)dimethylsilyl]-2''-fluoro-2''-methyl-P-phenyl-5''-uridylyl]-L-alanine 1-Methylethyl Ester Basic information
Product Name:N-[[P(S),2''R]-2''-deoxy-3''-O-[(1,1-dimethylethyl)dimethylsilyl]-2''-fluoro-2''-methyl-P-phenyl-5''-uridylyl]-L-alanine 1-Methylethyl Ester
Synonyms:N-[[P(S),2''R]-2''-deoxy-3''-O-[(1,1-dimethylethyl)dimethylsilyl]-2''-fluoro-2''-methyl-P-phenyl-5''-uridylyl]-L-alanine 1-Methylethyl Ester;L-Alanine, N-[[P(S),2'R]-2'-deoxy-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-, 1-methylethyl ester;-deoxy-3’-fluoro-2’-methyl-P-phenyl-5’N-[[P(S),2’-O-[(1,1-dimethylethyl)dimethylsilyl]-2’-uridylyl]-L-alanine1-MethylethylEster
CAS:1256490-54-6
MF:C28H43FN3O9PSi
MW:643.72
EINECS:
Product Categories:
Mol File:1256490-54-6.mol
N-[[P(S),2''R]-2''-deoxy-3''-O-[(1,1-dimethylethyl)dimethylsilyl]-2''-fluoro-2''-methyl-P-phenyl-5''-uridylyl]-L-alanine 1-Methylethyl Ester Structure
N-[[P(S),2''R]-2''-deoxy-3''-O-[(1,1-dimethylethyl)dimethylsilyl]-2''-fluoro-2''-methyl-P-phenyl-5''-uridylyl]-L-alanine 1-Methylethyl Ester Chemical Properties
density 1.24±0.1 g/cm3(Predicted)
solubility Chloroform, Dichloromethane, Methanol
form Solid
pka9.39±0.10(Predicted)
color White
Safety Information
MSDS Information
N-[[P(S),2''R]-2''-deoxy-3''-O-[(1,1-dimethylethyl)dimethylsilyl]-2''-fluoro-2''-methyl-P-phenyl-5''-uridylyl]-L-alanine 1-Methylethyl Ester Usage And Synthesis
UsesN-[[P(S),2''R]-2''-deoxy-3''-O-[(1,1-dimethylethyl)dimethylsilyl]-2''-fluoro-2''-methyl-P-phenyl-5''-uridylyl]-L-alanine 1-Methylethyl Ester is an intermediate in the synthesis of Sofosbuvir (R)-Phosphate (S675615), which is an impurity of PSI-7977 (P839640), a prodrug that is metabolized to the active antiviral agent 2''-deoxy-2''-α-fluoro-β-C-methyluridine-5''-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.
N-[[P(S),2''R]-2''-deoxy-3''-O-[(1,1-dimethylethyl)dimethylsilyl]-2''-fluoro-2''-methyl-P-phenyl-5''-uridylyl]-L-alanine 1-Methylethyl Ester Preparation Products And Raw materials
Tag:N-[[P(S),2''R]-2''-deoxy-3''-O-[(1,1-dimethylethyl)dimethylsilyl]-2''-fluoro-2''-methyl-P-phenyl-5''-uridylyl]-L-alanine 1-Methylethyl Ester(1256490-54-6) Related Product Information