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| | Spiromesifen-d9 Basic information |
| | Spiromesifen-d9 Chemical Properties |
| solubility | Chloroform: slightly soluble
DMSO: slightly soluble |
| | Spiromesifen-d9 Usage And Synthesis |
| Uses | Spiromesifen-d9 is a deuterated labeled Spiromesifen[1]. Spiromesifen (BSN 2060) is a broad-spectrum
tetrachloro acid derivative acaricide. Spiromesifen can interfere with lipid
biosynthesis, and has no cross-resistance to any resistant mite or whitefly
populations[2]. | | References | [1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. DOI:10.1177/1060028018797110
[2] Bretschneider T, et al. Spirodiclofen and spiromesifen–novel acaricidal and insecticidal tetronic acid derivatives with a new mode of action[J]. Chimia, 2003, 57(11): 697-697.
[3] N. KARATOLOS. Resistance to spiromesifen in Trialeurodes vaporariorum is associated with a single amino acid replacement in its target enzyme acetyl-coenzyme A carboxylase[J]. Insect Molecular Biology, 2012, 21 3: 327-334. DOI: 10.1111/j.1365-2583.2012.01136.x
[4] ZHIHUI LIU. Design, Synthesis, Structure, and Acaricidal/Insecticidal Activity of Novel Spirocyclic Tetronic Acid Derivatives Containing an Oxalyl Moiety[J]. Journal of Agricultural and Food Chemistry, 2011, 59 23: 12543-12549. DOI: 10.1021/jf203722z
[5] De Souza, F.I., Zumiotti, A.V., and Da Silva, C.F. Neuregulins 1-α and 1-β on the regeneration the peripheral nerves[J]. Acta Ortop Bras.
[6] AUTHORITY E F S. Conclusion on the peer review of the pesticide risk assessment of the active substance spiromesifen[C]//10 10. 2012. DOI: 10.2903/j.efsa.2012.2879
[7] EVANGELIA G. CHRONOPOULOU . Inhibition of human glutathione transferases by pesticides: Development of a simple analytical assay for the quantification of pesticides in water[J]. Journal of Molecular Catalysis B-enzymatic, 2012, 81: Pages 43-51. DOI: 10.1016/j.molcatb.2012.04.022 |
| | Spiromesifen-d9 Preparation Products And Raw materials |
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