Coumarin-Quinone Conjugate

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Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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CAS:2741190-31-6
Purity:95% Package:500μg;1mg;5mg
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Coumarin-Quinone Conjugate Basic information
Product Name:Coumarin-Quinone Conjugate
Synonyms:Coumarin-Quinone Conjugate;2H-1-Benzopyran-3-carboxylic acid, 7-(diethylamino)-2-oxo-, (2,4,5-trimethyl-3,6-dioxo-1,4-cyclohexadien-1-yl)methyl ester
CAS:2741190-31-6
MF:C24H25NO6
MW:423.46
EINECS:
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Mol File:2741190-31-6.mol
Coumarin-Quinone Conjugate Structure
Coumarin-Quinone Conjugate Chemical Properties
Boiling point 602.226±55.00 °C(Press: 760.00 Torr)(predicted)
density 1.254±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
solubility DMSO: soluble
Ethanol: soluble
pka2.769±0.20(predicted)
Safety Information
MSDS Information
Coumarin-Quinone Conjugate Usage And Synthesis
UsesCoumarin–quinone conjugate is a fluorescent substrate for NADH:ubiquinone oxidoreductases which consists of a coumarin fluorophore and a ubiquinone analog. Coumarin–quinone conjugate can be used to measure the kinetic parameters of AIFM2/FSP1 for researches such as ferroptosis[1].
References[1] Doll S, et al. FSP1 is a glutathione-independent ferroptosis suppressor. Nature. 2019 Nov;575(7784):693-698. DOI:10.1038/s41586-019-1707-0
[2] JOSEPH M. HENDRICKS. Identification of structurally diverse FSP1 inhibitors that sensitize cancer cells to ferroptosis[J]. bioRxiv : the preprint server for biology, 2022, 6 1. DOI: 10.1101/2022.12.14.520445
Coumarin-Quinone Conjugate Preparation Products And Raw materials
Tag:Coumarin-Quinone Conjugate(2741190-31-6) Related Product Information
7-Benzyloxy-4-(trifluoromethyl)coumarin 7-ETHOXY-4-(TRIFLUOROMETHYL)COUMARIN D-ALPHA-TOCOPHERYLQUINONE 7-METHOXY-4-(TRIFLUOROMETHYL)COUMARIN FCCP CARBONYL CYANIDE 3-CHLOROPHENYLHYDRAZONE