α-MSH (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt) manufacturers
- α-MSH TFA
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- $72.00
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2026-07-21
- CAS:171869-93-5
- Purity:
- Supply Ability: 10g
- α-MSH TFA
-
- $72.00
-
2026-01-05
- CAS:171869-93-5
- Purity:
- Supply Ability: 10g
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| | α-MSH (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt) Basic information |
| Product Name: | α-MSH (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt) | | Synonyms: | α-MSH (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt);α-Melanocyte-Stimulating Hormone (MSH), amide TFA;α-MSH (human, mouse, rat, porcine, bovine, ovine) trifluoroacetate salt;(4S,7S,10S,13S,16S,22S)-7-((1H-imidazol-5-yl)methyl)-16-((1H-indol-3-yl)methyl)-26-amino-22-((S)-2-(((S)-1-amino-3-methyl-1-oxobutan-2-yl)carbamoyl)pyrrolidine-1-carbonyl)-10-benzyl-13-(3-guanidinopropyl)-4-((2S,5S,8S,11S)-8-(4-hydroxybenzyl)-5,11-bis(hydroxymethyl)-2-(2-(methylthio)ethyl)-4,7,10,13-tetraoxo-3,6,9,12-tetraazatetradecanamido)-5,8,11,14,17,20-hexaoxo-6,9,12,15,18,21-hexaazahexacosan-1-oic acid compound with 2,2,2-trifluoroacetic acid (1:1);L-Valinamide, N-acetyl-L-seryl-L-tyrosyl-L-seryl-L-methionyl-L-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophylglycyl-L-lysyl-L-prolyl-xTFA salt;α-MSH TFA;I-Msh (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt);(4S,7S,10S,13S,16S,22S)-7-((1H-Imidazol-4-yl)methyl)-16-((1H-indol-3-yl)methyl)-26-amino-22-((S)-2-(((S)-1-amino-3-methyl-1-oxobutan-2-yl)carbamoyl)pyrrolidine-1-carbonyl)-10-benzyl-13-(3-guanidinopropyl)-4-((2S,5S,8S,11S)-8-(4-hydroxybenzyl)-5,11-bis(hydroxymethyl)-2-(2-(methylthio)ethyl)-4,7,10,13-tetraoxo-3,6,9,12-tetraazatetradecanamido)-5,8,11,14,17,20-hexaoxo-6,9,12,15,18,21-hexaazahexacosanoic acid compound with 2,2,2-trifluoroacetic acid (1:X) | | CAS: | 171869-93-5 | | MF: | C79H110F3N21O21S | | MW: | 1778.93 | | EINECS: | | | Product Categories: | | | Mol File: | 171869-93-5.mol |  |
| | α-MSH (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt) Chemical Properties |
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C | | solubility | DMF: 10mg/mL,DMSO: 25mg/mL,DMSO:PBS (pH 7.2) (1:5): 0.16mg/mL | | form | A solid | | color | White to off-white | | Sequence | Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2 |
| | α-MSH (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt) Usage And Synthesis |
| Uses | α-MSH (α-Melanocyte-Stimulating Hormone) TFA, an endogenous neuropeptide, is an endogenous melanocortin receptor 4 (MC4R) agonist with anti-inflammatory and antipyretic activities. α-MSH TFA is a post-translational derivative of pro-opiomelanocortin (POMC)[1][2]. | | in vivo | α-MSH TFA (50 μg/0.2 ml saline; i.p.) given systemically effectively modulates inflammatory reactions[3]. | | IC 50 | MC4R | | References | [1] Madhuri Singh, et al. C-terminal amino acids of alpha-melanocyte-stimulating hormone are requisite for its antibacterial activity against Staphylococcus aureus. Antimicrob Agents Chemother. 2011 May;55(5):1920-9. DOI:10.1128/AAC.00957-10
[2] 2. M S Kim, et al. Hypothalamic localization of the feeding effect of agouti-related peptide and alpha-melanocyte-stimulating hormone. Diabetes. 2000 Feb;49(2):177-82. DOI:10.2337/diabetes.49.2.177
[3] Lipton JM, et al. Mechanisms of antiinflammatory action of alpha-MSH peptides. In vivo and in vitro evidence. Ann N Y Acad Sci. 1999;885:173-182. DOI:10.1111/j.1749-6632.1999.tb08674.x |
| | α-MSH (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt) Preparation Products And Raw materials |
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