(S)-3-Phenylbutyric acid

(S)-3-Phenylbutyric acid Suppliers list

Company Name:	Amadis Chemical Company Limited
Tel:	571-89925085
Email:	sales@amadischem.com

(S)-3-Phenylbutyric acid manufacturers

(S)-3-Phenylbutyric acid Basic information

Product Name:	(S)-3-Phenylbutyric acid
Synonyms:	(s)-β-methylhydrocinnamic acid;(3S)-3-Phenylbutanoic acid;(3S)-3-Phenylbutyric acid;(S)-3-Phenylisobutyric acid;(S)-α-Methylbenzenepropionic acid;[S,(+)]-2-Benzylpropionic acid;[S,(+)]-2-Methyl-3-phenylpropionic acid;(S)-BETA-METHYLHYDROCINNAMIC ACID
CAS:	772-15-6
MF:	C10H12O2
MW:	164.2
EINECS:
Product Categories:
Mol File:	772-15-6.mol

(S)-3-Phenylbutyric acid Chemical Properties

Boiling point	94-95 °C0.3 mm Hg(lit.)
density	1.069 g/mL at 20 °C(lit.)
refractive index	n20/D 1.518
pka	4.67±0.10(Predicted)
form	liquid
Optical Rotation	[α]20/D +57±2°, c =1% in benzene
InChI	1S/C10H12O2/c1-8(7-10(11)12)9-5-3-2-4-6-9/h2-6,8H,7H2,1H3,(H,11,12)/t8-/m0/s1
InChIKey	ZZEWMYILWXCRHZ-QMMMGPOBSA-N
SMILES	C[C@@H](CC(O)=O)c1ccccc1

Safety Information

MSDS Information

Provider	Language
SigmaAldrich	English

(S)-3-Phenylbutyric acid Usage And Synthesis

Chemical Properties	optical purity >99%
Uses	(S)-3-Phenylbutyric Acid is used as a sole carbon and energy source in the isolation of Rhodococcus rhodochrous PB1 from compost soil.Also, it is used in the design and synthesis of 2-Acylaminopyridin-4-ylimidazoles as p38 MAP kinase inhibitors in the treatment of many inflammatory disorders.
Purification Methods	Purify the acids as the 2-isomer above, i.e. by distillation, but under a good vacuum. [Prelog & Scherrer Helv Chim Acta 42 2227 1959, Levene & Marker J Biol Chem 93 761 1932, 100 685 1933, Cram J Am Chem Soc 74 2137 1952.] The R-amide crystallises from H2O, with m 101.5-102o, and [] 20 -16.5o (c 1.2, EtOH). The racemic acid has m 39-40o, b 134-136o/6mm, 158o/12mm [Marvel et al. J Am Chem Soc 62 3499 1940]. [Beilstein 9 IV 1813.]

(S)-3-Phenylbutyric acid Preparation Products And Raw materials

Tag:(S)-3-Phenylbutyric acid(772-15-6) Related Product Information

ethyl 4-bromo-4-phenyl-butanoate 2-Phenylbutyric acid ethyl ester (S)-3-(Fmoc-amino)-4-phenylbutyric acid, Fmoc-L-β-homophenylalanine 4-(4-Aminophenyl)butyric acid 2-Phenylbutyric acid Boc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid Boc-(R)-3-amino-4-(2-fluoro-phenyl)-butyric acid Fmoc-(S)-3-amino-4-(4-fluoro-phenyl)-butyric acid Fmoc-(R)-3-amino-4-(3-methyl-phenyl)-butyric acid 3-Amino-4-(3-methoxyphenyl)butanoic acid (S)-3-Amino-4-(4-methoxyphenyl)butanoic acid 3-Phenylbutyric acid Fmoc-(S)-3-amino-4-(3-methyl-phenyl)-butyric acid Fmoc-(S)-3-amino-4-(4-bromo-phenyl)-butyric acid Fmoc-(S)-3-amino-4-(3-fluoro-phenyl)-butyric acid Fmoc-(R)-3-amino-4-(4-nitro-phenyl)-butyric acid Boc-(S)-3-amino-4-(4-nitro-phenyl)-butyric acid Fmoc-(S)-3-amino-4-(4-nitro-phenyl)-butyric acid