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| | 2,3,6-trichlorophenol Basic information |
| Product Name: | 2,3,6-trichlorophenol | | Synonyms: | 2,3,6-trichloro-pheno;Phenol, 2,3,6-trichloro-;2,3,6-TRICHLOROPHENOL;Trichlorophenol, 2,3,6-;2,3,6-TRICHLOROPHENOL PESTANAL, 250 MG;2,3,6-TRICHLOROPHENOL, 100MG, NEAT;2,3,6-Trichlorophenol,98%;2.3.6-Trichlorophenol 1g [933-75-5] | | CAS: | 933-75-5 | | MF: | C6H3Cl3O | | MW: | 197.45 | | EINECS: | 213-271-7 | | Product Categories: | T-ZAlphabetic;Pesticides&Metabolites;Q-ZAlphabetic;Alpha Sort;Chemical Class;ChloroAnalytical Standards;Halogenated;PhenolsVolatiles/ Semivolatiles;TP - TZ | | Mol File: | 933-75-5.mol |  |
| | 2,3,6-trichlorophenol Chemical Properties |
| Melting point | 53-55 °C(lit.) | | Boiling point | 88 °C (0.4 mmHg) | | density | 1.5 g/cm3 | | refractive index | 1.5300 (estimate) | | Fp | 78 °C | | storage temp. | Sealed in dry,Room Temperature | | solubility | methanol: 0.1 g/mL, clear | | pka | 6.06±0.15(Predicted) | | color | Colorless needles from pet ether | | Water Solubility | 591mg/L(25 ºC) | | BRN | 1867596 | | Stability: | Stability Combustible. Incompatible with strong oxidizing agents, acid anhydrides, acid chlorides. May be hygroscopic. | | InChI | InChI=1S/C6H3Cl3O/c7-3-1-2-4(8)6(10)5(3)9/h1-2,10H | | InChIKey | XGCHAIDDPMFRLJ-UHFFFAOYSA-N | | SMILES | C1(O)=C(Cl)C=CC(Cl)=C1Cl | | CAS DataBase Reference | 933-75-5(CAS DataBase Reference) | | EPA Substance Registry System | 2,3,6-Trichlorophenol (933-75-5) |
| Hazard Codes | Xn | | Risk Statements | 22-36/38 | | Safety Statements | 26-28 | | RIDADR | UN 2020 6.1/PG 3 | | WGK Germany | 3 | | RTECS | SN1300000 | | TSCA | TSCA listed | | HazardClass | 6.1(b) | | PackingGroup | III | | HS Code | 2908190090 | | Hazardous Substances Data | 933-75-5(Hazardous Substances Data) | | Toxicity | mmo-sat 10 mg/plate TECSDY 14,143,87 |
| | 2,3,6-trichlorophenol Usage And Synthesis |
| Chemical Properties | off-white, light tan to purple crystals | | General Description | Colorless needles or purple crystalline solid. Taste threshold concentration: 0.0005 mg/L. Odor threshold concentration (detection): 0.3 mg. | | Air & Water Reactions | May be hygroscopic. Insoluble in water. | | Reactivity Profile | 2,3,6-TRICHLOROPHENOL is incompatible with acid chlorides, acid anhydrides and oxidizing agents. . | | Fire Hazard | 2,3,6-TRICHLOROPHENOL is combustible. | | Safety Profile | Poison by intraperitoneal route.Mutation data reported. When heated to decomposition itemits toxic fumes of Clí. | | Degradation |
LAC-4 (a laccase purified from Ganoderma lucidum) had a strong ability for 2,6- dichlorophenol (2,6-DCP) and 2,3,6-trichlorophenol (2,3,6-TCP) degradation. LAC-4 also had a good degradation effect on the chlorophenol mixture (2,6-DCP + 2,3,6-TCP). The results of the kinetics of the degradation of chlorophenols by LAC-4 suggested that the affinity of LAC-4 for 2,6-DCP was higher than that of 2,3,6-TCP. The catalytic efficiency and the catalytic rate of LAC-4 on 2,6-DCP were also significantly higher than 2,3,6-TCP. During the degradation of 2,6-DCP and 2,3,6-TCP, LAC-4 had a strong tolerance for high concentrations of different metal salts (such as MnSO4, ZnSO4, Na2SO4, MgSO4, CuSO4, K2SO4 ) and organic solvents (such as ethylene glycol and glycerol). The free radicals formed by LAC-4 oxidation of 2,6-DCP and 2,3,6-TCP produced dimers through polymerization. LAC-4 catalyzed the polymerization of 2,6-DCP and 2,3,6-TCP, forming dimer products. LAC-4 catalyzed 2,3,6-TCP into two main products: 2,3,6-trichloro-4-(2,3,6- trichlorophenoxy) phenol and 2,2',3,3',5,5' -hexachloro-[1,1' -biphenyl]-4,4' -diol[1].
| | References | [1] Wei Deng, Yang Yang, Wei Zhao. “Degradation and Detoxification of Chlorophenols with Different Structure by LAC-4 Laccase Purified from White-Rot Fungus Ganoderma lucidum.” International Journal of Environmental Research and Public Health (2022).
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| | 2,3,6-trichlorophenol Preparation Products And Raw materials |
| Raw materials | 2,3,4-TRICHLOROANISOLE-->2,3,4-TRICHLOROPHENOL-->2,3,4,6-TETRACHLOROPHENOL-->2,3,5,6-TETRACHLOROPHENOL-->2,3,5-TRICHLOROPHENOL-->1,2,3,4-Tetrachlorobenzene-->Pentachlorophenol-->Sodium Methoxide-->2,4,5-Trichlorophenol-->2,4,6-Trichlorophenol | | Preparation Products | 2,3,6-TRICHLOROPHENOL ACETATE |
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