- L-Asp(OMe)-OMeHCl
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- $0.00/ kg
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2026-03-03
- CAS:32213-95-9
- Min. Order: 1kg
- Purity: 98%
- Supply Ability: 1T+
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| | Dimethyl L-aspartate hydrochloride Basic information |
| | Dimethyl L-aspartate hydrochloride Chemical Properties |
| Melting point | 115-117 °C(lit.) | | alpha | 15 º (c=1, MeOH) | | refractive index | 12 ° (C=1.4, H2O) | | storage temp. | Inert atmosphere,2-8°C | | solubility | DMSO (Slightly), Methanol (Slightly), Water (Slightly) | | form | Powder | | color | White to Off-white | | Water Solubility | Soluble in water (almost transparency) and methanol. | | Major Application | peptide synthesis | | InChI | InChI=1/C6H11NO4.ClH/c1-10-5(8)3-4(7)6(9)11-2;/h4H,3,7H2,1-2H3;1H/t4-;/s3 | | InChIKey | PNLXWGDXZOYUKB-WCCKRBBISA-N | | SMILES | [C@@H](N)(C(=O)OC)CC(=O)OC.Cl |&1:0,r| | | CAS DataBase Reference | 32213-95-9(CAS DataBase Reference) |
| Safety Statements | 24/25 | | WGK Germany | 3 | | HS Code | 29224999 | | Storage Class | 11 - Combustible Solids |
| | Dimethyl L-aspartate hydrochloride Usage And Synthesis |
| Chemical Properties | white to off-white crystalline powder | | Uses | Dimethyl L-Aspartate Hydrochloride was used in the synthesis of enzyme and pH dual responsive L-amino acid based biodegradable polymer nanocarrier that can be used for multidrug delivery to cancer cells. | | reaction suitability | reaction type: solution phase peptide synthesis | | Synthesis | Example 1; This example demonstrates the synthesis of dimethyl (S)-2-aminosuccinate hydrochloride from L-aspartic acid. The steps were as follows: a solution of L-aspartic acid (13.5 g, 100 mmol) dissolved in 100 ml of methanol was slowly added dropwise to pure thionyl chloride, and the reaction mixture was stirred continuously for 48 hours at room temperature. After completion of the reaction, the reaction mixture was concentrated in vacuum using a rotary evaporator. Subsequently, it was extracted and washed by adding methanol (3 x 30 ml) and dichloromethane (3 x 30 ml) to finally obtain L-aspartic acid dimethyl ester hydrochloride (19.5 g, quantitative yield) in white powder form. | | References | [1] Organic and Biomolecular Chemistry, 2009, vol. 7, # 20, p. 4309 - 4316
[2] Patent: US2007/142467, 2007, A1. Location in patent: Page/Page column 5
[3] Chemical Communications, 2011, vol. 47, # 23, p. 6569 - 6571
[4] Journal of Medicinal Chemistry, 2012, vol. 55, # 23, p. 10460 - 10474
[5] Organic and Biomolecular Chemistry, 2015, vol. 13, # 15, p. 4514 - 4523 |
| | Dimethyl L-aspartate hydrochloride Preparation Products And Raw materials |
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