EC 2.6.1.2 manufacturers
- EC 2.6.1.2
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- $1.00
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2020-01-13
- CAS:9000-86-6
- Min. Order: 1KG
- Purity: 98%HPLC
- Supply Ability: 10tons
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| | EC 2.6.1.2 Chemical Properties |
| storage temp. | -70°C | | form | suspension (aqueous) | | color | green-yellow | | biological source | Porcine heart | | Water Solubility | Dissolves readily at 5 mg/ml in 0.05M potassium phosphate pH 7.5 to give a clear, pale-green solution. Soluble in distilled water or dilute buffer. | | BRN | 3562140 | | Specific Activity | ≥75units/mg protein | | InChI | InChI=1S/C11H16N2O6/c1-5-3-13(11(18)12-10(5)17)8-2-6(15)9(16)7(4-14)19-8/h3,6-9,14-16H,2,4H2,1H3,(H,12,17,18) | | InChIKey | VVJYUAYZJAKGRQ-UHFFFAOYSA-N | | SMILES | C1(=O)N(C2CC(O)C(O)C(CO)O2)C=C(C)C(=O)N1 | | EPA Substance Registry System | Aminotransferase, alanine (9000-86-6) |
| WGK Germany | 3 | | F | 10 | | TSCA | TSCA listed | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Resp. Sens. 1 |
| | EC 2.6.1.2 Usage And Synthesis |
| Uses | It is used for research and clinical diagnostic assays for liver disease. Alanine transaminase (GPT/ALT) is used in multi-analyte clinical chemistry controls and calibrators for major IVD manufacturers. The alanine aminotransferase (ALT) blood test is typically used to detect liver injury. Some of the other applications include Diagnostic Controls, calibrators & standards, immunoassays, clinical chemistry, testing/assay validation, life Science, manufacturing, validation Studies. | | General Description | Glutamic-pyruvic transaminase (GPT) is localized majorly in the liver. | | Biochem/physiol Actions | Glutamic-pyruvic transaminase (GPT) mediates the transfer of the amino group to α-ketoglutarate from l-alanine. It plays a key role in gluconeogenesis and amino acid metabolism. The role of GPT in various kinds of tumors has been reported. | | Description | GPT Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 516 amino acids (1-496) and having a molecular mass of 56.8 kDa.
GPT is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. | | Source | Ecoli | | Background | GPT catalyzes the reversible transamination between alanine and 2-oxoglutarate to create pyruvate and glutamate. GPT has a crucial part in the intermediary metabolism of glucose and amino acids. GPT is broadly used as an indicator of liver reliability or hepatocellular destruction in clinical tests. |
| | EC 2.6.1.2 Preparation Products And Raw materials |
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