3-Bromo-3,3-difluoropropene manufacturers
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| | 3-Bromo-3,3-difluoropropene Basic information |
| Product Name: | 3-Bromo-3,3-difluoropropene | | Synonyms: | 3,3-DIFLUORO-3-BROMOPROPENE;1-BROMO-1,1-DIFLUOROPROP-2-ENE;1-BROMO-1,1-DIFLUOROPROPENE;3-Bromo-3,3-difluoroprop-1-ene 98%;3-Bromo-3,3-difluoroprop-1-ene98%;1,1-Difluoroallyl bromide;1-Bromo-1,1-difluoro-2-propene;3,3-Difluoro-3-bromo-1-propene | | CAS: | 420-90-6 | | MF: | C3H3BrF2 | | MW: | 156.96 | | EINECS: | 810-594-0 | | Product Categories: | | | Mol File: | 420-90-6.mol |  |
| | 3-Bromo-3,3-difluoropropene Chemical Properties |
| Melting point | 53-54°C | | Boiling point | 41-42°C | | density | 1,543 g/cm3 | | refractive index | 1.377 | | storage temp. | Keep Cold | | form | clear liquid | | Specific Gravity | 1.543 | | color | Colorless to Light yellow | | InChI | InChI=1S/C3H3BrF2/c1-2-3(4,5)6/h2H,1H2 | | InChIKey | GDDNTTHUKVNJRA-UHFFFAOYSA-N | | SMILES | C=CC(Br)(F)F | | CAS DataBase Reference | 420-90-6(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36/37/39 | | Hazard Note | Irritant | | HazardClass | IRRITANT, KEEP COLD | | HS Code | 2903793090 |
| | 3-Bromo-3,3-difluoropropene Usage And Synthesis |
| Uses |
3-Bromo-3,3-difluoropropene, when mixed with lithium bromide, provides a convenient route to prepare gem-(difluoroallyl) lithium, a reagent of general use in the formation of gem-difluorinated organic compounds. Umpolung asymmetric difluoroallylation of hydrazones with 3-bromo-3,3-difluoropropene (BDFP) under palladium catalysis. In addition, aldehydes and ketones reacted with 3-bromo-3,3-difluoropropene in the presence of the acid-washed zinc powder at 0°C to room temperature to afford gem-difluorohomoallyl alcohols in moderate yields[1-3].
| | References |
[1] Shuai Huang. “Regio- and enantioselective umpolung gem-difluoroallylation of hydrazones via palladium catalysis enabled by N-heterocyclic carbene ligand.” Nature Communications 12 1 (2021): 6551.
[2] J.D. Langridge, S.A. Cooke, B.E. Long. “The microwave spectra, bromine nuclear electric quadrupole coupling tensor, and structure of 3-bromo-3,3-difluoropropene.” Journal of Molecular Structure 1000 1 (2011): Pages 24-28.
[3] M. Kirihara. “Indium-Mediated Reaction of 3-Bromo-3,3-difluoropropene and Bromodifluoromethylacetylene Derivatives with Aldehydes.” ChemInform 3 1 (2001).
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| | 3-Bromo-3,3-difluoropropene Preparation Products And Raw materials |
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