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| | 3,3'-Dithiodipropionic acid Basic information |
| | 3,3'-Dithiodipropionic acid Chemical Properties |
| Melting point | 155-158 °C(lit.) | | Boiling point | 319.8°C (rough estimate) | | density | 1.319 (estimate) | | refractive index | 1.5220 (estimate) | | storage temp. | Sealed in dry,Room Temperature | | Water Solubility | Practically insoluble in water | | solubility | DMSO (Sparingly), Methanol (Slightly) | | form | Powder | | pka | 3.94±0.10(Predicted) | | color | White | | BRN | 1778543 | | InChI | InChI=1S/C6H10O4S2/c7-5(8)1-3-11-12-4-2-6(9)10/h1-4H2,(H,7,8)(H,9,10) | | InChIKey | YCLSOMLVSHPPFV-UHFFFAOYSA-N | | SMILES | S(CCC(O)=O)SCCC(O)=O | | CAS DataBase Reference | 1119-62-6(CAS DataBase Reference) | | EPA Substance Registry System | Propanoic acid, 3,3'-dithiobis- (1119-62-6) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | RIDADR | 1759 | | WGK Germany | 3 | | F | 13 | | TSCA | TSCA listed | | HazardClass | 8 | | PackingGroup | III | | HS Code | 29309090 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| | 3,3'-Dithiodipropionic acid Usage And Synthesis |
| Chemical Properties | white powder | | Uses | Highly reactive species. | | Uses | 3,3′-Dithiodipropionic acid was used as capping agent for introducing charge on gold nanoparticles surfaces. | | Synthesis Reference(s) | Tetrahedron, 41, p. 2903, 1985 DOI: 10.1016/S0040-4020(01)96614-1
Chemical and Pharmaceutical Bulletin, 34, p. 486, 1986 DOI: 10.1248/cpb.34.486 | | General Description | 3,3′-Dithiodipropionic acid forms monolayers on a polycrystalline gold electrode through a self-assembly procedure to form gold 3,3′-dithiodipropionic acid self-assembled monolayer modified electrode. It is the precursor substrate in the synthesis of 3-mercaptopropionic acid-containing polythioesters. It is added as primary carbon supplement in the culture medium of novel betaproteobacterium, strain DPN7. | | Research | Besides 3MP, also the organic sulfur compounds (OSCs) 3,3'-thiodipropionic acid (TDP) and 3,3'-dithiodipropionic acid (DTDP) are established precursor substrates for poly(3HB-co-3MP) biosynthesis in R. eutropha H16. Both precursors offer advantages in comparison to 3MP. While higher concentrations of 3MP seriously impair growth of R. eutropha H16, TDP and DTDP are nontoxic OSCs[1-2]. | | References |
[1] Christina Doberstein . “Polythioester synthesis in Ralstonia eutropha H16: Novel insights into 3,3′-thiodipropionic acid and 3,3′-dithiodipropionic acid catabolism.” Journal of biotechnology 184 (2014): Pages 187-198.
[2] Jan Hendrik Wübbeler. “Dihydrolipoamide dehydrogenases of Advenella mimigardefordensis and Ralstonia eutropha catalyze cleavage of 3,3’-dithiodipropionic acid into 3-mercaptopropionic acid.” ACS Applied Electronic Materials (2010): 7023–8.
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| | 3,3'-Dithiodipropionic acid Preparation Products And Raw materials |
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