- 2-Cyclopentenone
-
- $0.00 / 1kg
-
2023-12-04
- CAS:930-30-3
- Min. Order: 0.10000000149011612kg
- Purity: 98%
- Supply Ability: 100kg
- 2-Cyclopentenone
-
- $0.00 / 1kg
-
2023-12-04
- CAS:930-30-3
- Min. Order: 0.10000000149011612kg
- Purity: 98%
- Supply Ability: 100kg
- 2-Cyclopentenone
-
- $0.00 / 1KG
-
2022-02-22
- CAS:930-30-3
- Min. Order: 1KG
- Purity: 97.9%
- Supply Ability: 100 tons
|
| | 2-Cyclopenten-1-one Basic information |
| | 2-Cyclopenten-1-one Chemical Properties |
| Boiling point | 64-65 °C19 mm Hg(lit.) | | density | 0.98 g/mL at 25 °C(lit.) | | refractive index | n20/D 1.481(lit.) | | Fp | 108 °F | | storage temp. | 2-8°C | | solubility | soluble in Chloroform, Methanol | | form | Liquid | | color | Clear yellow | | Specific Gravity | 0.980 | | Water Solubility | almost insoluble | | BRN | 1446054 | | InChI | InChI=1S/C5H6O/c6-5-3-1-2-4-5/h1,3H,2,4H2 | | InChIKey | BZKFMUIJRXWWQK-UHFFFAOYSA-N | | SMILES | C1(=O)CCC=C1 | | LogP | -0.114 (est) | | CAS DataBase Reference | 930-30-3(CAS DataBase Reference) | | NIST Chemistry Reference | 2-Cyclopenten-1-one(930-30-3) |
| Hazard Codes | Xi,Xn | | Risk Statements | 10-37-36/37/38-22 | | Safety Statements | 16-36-36/37/39 | | RIDADR | UN 1224 3/PG 3 | | WGK Germany | 3 | | F | 8 | | Hazard Note | Irritant | | HazardClass | 3 | | PackingGroup | III | | HS Code | 29142990 |
| | 2-Cyclopenten-1-one Usage And Synthesis |
| Description | 2-Cyclopentenone contains two functional groups, a ketone and an alkene. It is a colourless liquid. 2-cyclopenten-1-one selectively induces the expression of the 70-kDa HSP (HSP70) in human cells through cycloheximide-sensitive activation of heat shock transcription factor 1 (HSF1). It is a natural product found in Perilla frutescens[1].
| | Chemical Properties | clear yellow liquid | | Uses | 2-Cyclopenten-1-one is a versatile electrophile employed in various addition reactions including conjugate addition of organocopper nucleophiles, Michael reaction with silyl enol ethers and siloxanes. It is also used in Diels-Alder cycloadditions and phosphoniosilylations. | | Definition | ChEBI: 2-cyclopenten-1-one is an enone that is cyclopentanone having a C=C double bond at position 2. It has a role as a Hsp70 inducer. It is an enone and an alicyclic ketone. | | Preparation | 2-Cyclopentenones can be synthesized in a number of ways. One of the routes involves elimination of α-bromo-cyclopentanone using lithium carbonate and Claisen condensation-decarboxylation-isomerization cascades of unsaturated diesters as shown below.
The acid-catalyzed dehydration of cyclopentanediols affords cyclopentenone.
As a functional group, the synthesis of 2-cyclopentenones is accomplished in a variety of other ways, including the Nazarov cyclization reaction from divinyl ketones, Saegusa–Ito oxidation from cyclopentanones, ring-closing metathesis from the corresponding dienes, oxidation of the corresponding cyclic allylic alcohols, and the Pauson–Khand reaction from alkenes, alkynes, and carbon monoxide.
en.wikipedia.org | | References | [1] A Rossi, M G Santoro, G Elia. “2-Cyclopenten-1-one, a new inducer of heat shock protein 70 with antiviral activity.” The Journal of Biological Chemistry 271 50 (1996): 32192–6.
|
| | 2-Cyclopenten-1-one Preparation Products And Raw materials |
|