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| | N,N-Diethyl-1,1,1-trimethylsilylamine Basic information |
| Product Name: | N,N-Diethyl-1,1,1-trimethylsilylamine | | Synonyms: | Silanamine, N,N-diethyl-1,1,1-trimethyl-;Silanamine,N,N-diethyl-1,1,1-trimethyl-;Trimethylsilyl-diethylamin;(Diethylamino)trimethylsilane, N-(Trimethylsilyl)diethylamine, TMSDEA;N,N-DiethylaminotrimethylsilaneTMSDEAN,N-Diethyltrimethylsilylamine;Trimethylsilyldiethylamine (TMSDEA);Diethyl(trimethylsilyl)amine;N,N-DIETHYLTRIMETHYLSILYLAMINE, DERIVATI ZATION GRADE | | CAS: | 996-50-9 | | MF: | C7H19NSi | | MW: | 145.32 | | EINECS: | 213-637-6 | | Product Categories: | Halogenated Heterocycles;Building Blocks;Chemical Synthesis;Nitrogen Compounds;Organic Building Blocks;Protected Amines;Aminosilanes;Analytical Chemistry;GC Derivatizing Reagents;Si (Classes of Silicon Compounds);Silicon Compounds (for Synthesis);Silylation (GC Derivatizing Reagents);Si-N Compounds;Synthetic Organic Chemistry;Trimethylsilylation (GC Derivatizing Reagents) | | Mol File: | 996-50-9.mol |  |
| | N,N-Diethyl-1,1,1-trimethylsilylamine Chemical Properties |
| Melting point | -10°C | | Boiling point | 125-126 °C(lit.) | | density | 0.767 g/mL at 25 °C(lit.) | | vapor density | >1 (vs air) | | refractive index | n20/D 1.411(lit.) | | Fp | 50 °F | | storage temp. | Keep in dark place,Inert atmosphere,2-8°C | | solubility | Chloroform (Sparingly), DMSO (Slightly), Ethyl Acetate (Slightly) | | pka | 11.27±0.70(Predicted) | | form | clear liquid | | color | Colorless to Light yellow | | Specific Gravity | 0.763 | | Water Solubility | decomposes | | Sensitive | Moisture Sensitive | | Hydrolytic Sensitivity | 7: reacts slowly with moisture/water | | BRN | 635718 | | CAS DataBase Reference | 996-50-9(CAS DataBase Reference) | | NIST Chemistry Reference | N,N-Diethyl-1,1,1-trimethylsilylamine(996-50-9) | | EPA Substance Registry System | Silanamine, N,N-diethyl-1,1,1-trimethyl- (996-50-9) |
| | N,N-Diethyl-1,1,1-trimethylsilylamine Usage And Synthesis |
| Chemical Properties | Colorless liquid | | Uses | Trimethylsilyldiethylamine is a reagent used as an electrophilic trimethylsilyl source for cleavage
of cyclic ethers, esters, oxazolidines, and cyclic acetals; also as a nucleophilic source of the diethylamino group, participating in the following synthesis reactions: Trimethylsilyl Group Transfer, Diethylamino Group Transfer, Trimethylsilyldiethylamine as Halosilane Equivalent, Silylation of Alcohols, Mild Generation of Phosphonochloridates, Silylation of Amines, Diethylamino Group Transfer, Conjugate Addition, Aminoalkylation of Aldehydes, Enamine and Silyl Enol Ether Preparation, Mediation of 1,4-Conjugate Additions, etc. | | Uses | It is used to derivative polar organic compounds. N,N-Diethyl(trimethylsilyl)amine is a chemical reagent with wide application in organic chemistry and used in stereo specific addition reactions as well as in SN2 nucleophilic substitutions. | | Definition | ChEBI: An N-silyl compound that is diethylamine in which the amino hydrogen is replaced by a trimethylsilyl group. N-(trimethylsilyl)diethylamine is a derivatisation agent used in gas chromatography/mass spectrometry applicat
ons. | | General Description | N,N-Diethyltrimethylsilylamine is a silylating agent used to derivatize polar organic compounds. | | Purification Methods | Fractionate it through a 2ft vacuum-jacketed column containing Helipak packing with a reflux ratio of 10:1. [Sauer & Hasek J Am Chem Soc 68 241 1946, Langer et al. J Org Chem 23 50 1958, Rühlmann J Prakt Chem 9 315 1959, Beilstein 4 IV 4010.] |
| | N,N-Diethyl-1,1,1-trimethylsilylamine Preparation Products And Raw materials |
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