1,2-DI[(CIS)-9-OCTADECENOYL]-SN-GLYCEROL-3-PHOSPHO-[1-RAC-GLYCEROL] SODIUM SALT manufacturers
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| | 1,2-DI[(CIS)-9-OCTADECENOYL]-SN-GLYCEROL-3-PHOSPHO-[1-RAC-GLYCEROL] SODIUM SALT Basic information |
| Product Name: | 1,2-DI[(CIS)-9-OCTADECENOYL]-SN-GLYCEROL-3-PHOSPHO-[1-RAC-GLYCEROL] SODIUM SALT | | Synonyms: | 1,2-Dioleoyl-sn-glycero-3-phospho-rac-(1-glycerol) Sodium Sal;1,2-Dioleoyl-sn-glycero-3-phospho-rac-(1-glycerol) sodium salt(DOPG);DOPG;L-ALPHA-PHOSPHATIDYL-DL-GLYCEROL, DIOLEOYL SODIUM SALT;1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHO-RAC-GLYCEROL SODIUM SALT;1,2-DIELAIDOYL-SN-GLYCERO-3-[PHOSPHO-RAC-(1-GLYCEROL)] (SODIUM SALT);1,2-DI[(CIS)-9-OCTADECENOYL]-SN-GLYCEROL-3-PHOSPHO-[1-RAC-GLYCEROL] SODIUM SALT;18:1 TRANS PG (SODIUM SALT) | | CAS: | 67254-28-8 | | MF: | C42H80NaO10P | | MW: | 799.06 | | EINECS: | 200-663-8 | | Product Categories: | | | Mol File: | 67254-28-8.mol | ![1,2-DI[(CIS)-9-OCTADECENOYL]-SN-GLYCEROL-3-PHOSPHO-[1-RAC-GLYCEROL] SODIUM SALT Structure](CAS/GIF/67254-28-8.gif) |
| | 1,2-DI[(CIS)-9-OCTADECENOYL]-SN-GLYCEROL-3-PHOSPHO-[1-RAC-GLYCEROL] SODIUM SALT Chemical Properties |
| Fp | >200℃ | | storage temp. | -20°C | | solubility | Chloroform: 2 mg/ml | | form | solution | | color | White to Almost white | | biological source | synthetic | | InChIKey | IUVFCFQZFCOKRC-PDSLQGCUSA-M | | SMILES | [C@H](COC(=O)CCCCCCC/C=C\CCCCCCCC)(OC(=O)CCCCCCC/C=C\CCCCCCCC)COP(O)(=O)OCC(O)CO.[NaH] |&1:0,r| |
| | 1,2-DI[(CIS)-9-OCTADECENOYL]-SN-GLYCEROL-3-PHOSPHO-[1-RAC-GLYCEROL] SODIUM SALT Usage And Synthesis |
| Description | 1,2-Dioleoyl-sn-glycero-3-PG (DOPG) is a phospholipid containing the long-chain (18:1) fatty acid oleic acid inserted at the sn-1 and sn-2 positions. It can be used in the generation of micelles, liposomes, and other artificial membranes. | | Uses | 18:1 (Δ9-Cis) PG has been used:
- in the preparation of giant unilamellar vesicle (GUV)
- in the preparation 200 nm large unilamellar vesicles (LUV)
- as a supplement in native macrophage membranes to generate membrane liposomes with an artificially modified electrical charge
| | Uses | 1,2-Dioleoyl-sn-glycero-3-phospho-rac-(1-glycerol) is an analog of 1,2-Dipalmitoyl-sn-glycero-3-phospho-rac-(1-glycerol) (D525495) which forms lipid bilayers. In the high temperature phase, the conformation of the chains is liquid-like. In the low temperature phases, the chains are stiff and parallel and they interdigitate. | | General Description | Phosphoglyceride (PG) are also referred as glycerophospholipid. It is an important component of membrane?bilayers. It has three-carbon backbone of glycerol, two long-chain?fatty acids,?esterified to?hydroxyl groups on carbons 1 and 2 of the glycerol and?phosphoric acid?esterified to the C3?hydroxyl group of glycerol. It is found at high levels in the membranes of all cells and at low levels in fat stores. 1,2-dioleoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (DOPG)/18:1 (Δ9-Cis) PG?has two hydroxyl groups in its head group. It is an anionic lipid. | | Biochem/physiol Actions | Remodeling of diacylphosphatidylglycerols by transesterification was studied in a phosphatidylglycerol-deficient microbe grown with exogenous DOPG. | | References | [1] TOMOYOSHI TAKAHASHI. Multiple membrane interactions and versatile vesicle deformations elicited by melittin.[J]. Toxins, 2013: 637-664. DOI: 10.3390/toxins5040637
[2] CíNTIA C. VEQUI-SUPLICY . Vesicles with charged domains[J]. Biochimica et biophysica acta. Biomembranes, 2010, 1798 7: Pages 1338-1347. DOI: 10.1016/j.bbamem.2009.12.023 |
| | 1,2-DI[(CIS)-9-OCTADECENOYL]-SN-GLYCEROL-3-PHOSPHO-[1-RAC-GLYCEROL] SODIUM SALT Preparation Products And Raw materials |
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