3,6,9-Trioxa-12-azapentadecanoic acid, 15-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-13-oxo-, 2,5-dioxo-1-pyrrolidinyl ester

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3,6,9-Trioxa-12-azapentadecanoic acid, 15-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-13-oxo-, 2,5-dioxo-1-pyrrolidinyl ester Suppliers list
Company Name: Hangzhou MolCore BioPharmatech Co.,Ltd.
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Products Intro: Product Name:Mal-amido-PEG3-C1-NHS ester
CAS:2101206-45-3
Purity:95%+ Remarks:MC738863
Company Name: Beijing Jin Ming Biotechnology Co., Ltd.  
Tel: 010-60605840 18892239720
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Products Intro: Product Name:Mal-amido-PEG3-C1-NHS ester
CAS:2101206-45-3
Package:100mg;250mg;500mg
Company Name: Shanghai Yanfen Biochemical Technology Co.,LTD  
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Products Intro: Product Name:2,5-dioxopyrrolidin-1-yl 2-[2-(2-{2-[3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamido]ethoxy}ethoxy)ethoxy]acetate
CAS:2101206-45-3
Purity:>=95% Package:1g;5g;25g;100g;
Company Name: Henan Mengtai Pharmaceutical Technology Co., Ltd  
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Products Intro: Product Name:Mal-amido-PEG3-C1-NHS ester
CAS:2101206-45-3
Purity:98% HPLC
Company Name: MedChemExpress  
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Products Intro: Product Name:Mal-amido-PEG3-C1-NHS ester
CAS:2101206-45-3
3,6,9-Trioxa-12-azapentadecanoic acid, 15-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-13-oxo-, 2,5-dioxo-1-pyrrolidinyl ester Basic information
Product Name:3,6,9-Trioxa-12-azapentadecanoic acid, 15-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-13-oxo-, 2,5-dioxo-1-pyrrolidinyl ester
Synonyms:3,6,9-Trioxa-12-azapentadecanoic acid, 15-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-13-oxo-, 2,5-dioxo-1-pyrrolidinyl ester;Mal-amido-PEG3-C1-?NHS ester;2,5-dioxopyrrolidin-1-yl 2-[2-(2-{2-[3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamido]ethoxy}ethoxy)ethoxy]acetate
CAS:2101206-45-3
MF:C19H25N3O10
MW:455.42
EINECS:
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Mol File:2101206-45-3.mol
3,6,9-Trioxa-12-azapentadecanoic acid, 15-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-13-oxo-, 2,5-dioxo-1-pyrrolidinyl ester Structure
3,6,9-Trioxa-12-azapentadecanoic acid, 15-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-13-oxo-, 2,5-dioxo-1-pyrrolidinyl ester Chemical Properties
density 1.41±0.1 g/cm3(Predicted)
pka15.00±0.46(Predicted)
Safety Information
MSDS Information
3,6,9-Trioxa-12-azapentadecanoic acid, 15-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-13-oxo-, 2,5-dioxo-1-pyrrolidinyl ester Usage And Synthesis
UsesMal-amido-PEG3-C1- NHS ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
IC 50Non-cleavable Linker
References[1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268
3,6,9-Trioxa-12-azapentadecanoic acid, 15-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-13-oxo-, 2,5-dioxo-1-pyrrolidinyl ester Preparation Products And Raw materials
Tag:3,6,9-Trioxa-12-azapentadecanoic acid, 15-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-13-oxo-, 2,5-dioxo-1-pyrrolidinyl ester(2101206-45-3) Related Product Information