Uridine, 2'-O-[3-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)propyl]- (9CI) manufacturers
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| | Uridine, 2'-O-[3-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)propyl]- (9CI) Basic information |
| | Uridine, 2'-O-[3-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)propyl]- (9CI) Chemical Properties |
| density | 1.58±0.1 g/cm3(Predicted) | | pka | 9.39±0.10(Predicted) |
| | Uridine, 2'-O-[3-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)propyl]- (9CI) Usage And Synthesis |
| Uses | 2’-O-Phthalimidopropyl uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | | References | [1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
| | Uridine, 2'-O-[3-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)propyl]- (9CI) Preparation Products And Raw materials |
| Raw materials | N-(3-HYDROXYPROPYL)PHTHALIMIDE-->6H-Furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one, 2,3,3a,9a-tetrahydro-3-hydroxy-2-(hydroxymethyl)-, (2R,3R,3aR,9aR)- |
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